%0 Journal Article %A Matthew Matlock %A Na Le Dang %A David Brown %A S. Joshua Swamidass %T A Sign of Disparity: Racial/Ethnic Composition of Treatment Centers is an Independent Risk Factor in SPRINT Trial %D 2017 %R 10.1101/102111 %J bioRxiv %P 102111 %X The racial composition of treatment centers in the SPRINT trial is an independent risk factor for myocardial infarction (MI) and stroke. Independent of individual race or ethnicity, patients face a 39% increase in relative risk of MI or stroke when associated to treatment centers with a high proportion of African Americans. The magnitude of this effect is comparable to smoking. This suggests the strong influence of social determinants on health outcomes among hypertensive patients. %U https://www.biorxiv.org/content/biorxiv/early/2017/03/05/102111.full.pdf