TY - JOUR T1 - A Sign of Disparity: Racial/Ethnic Composition of Treatment Centers is an Independent Risk Factor in SPRINT Trial JF - bioRxiv DO - 10.1101/102111 SP - 102111 AU - Matthew Matlock AU - Na Le Dang AU - David Brown AU - S. Joshua Swamidass Y1 - 2017/01/01 UR - http://biorxiv.org/content/early/2017/03/05/102111.abstract N2 - The racial composition of treatment centers in the SPRINT trial is an independent risk factor for myocardial infarction (MI) and stroke. Independent of individual race or ethnicity, patients face a 39% increase in relative risk of MI or stroke when associated to treatment centers with a high proportion of African Americans. The magnitude of this effect is comparable to smoking. This suggests the strong influence of social determinants on health outcomes among hypertensive patients. ER -