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Page 1
Longitudinal molecular trajectories of diffuse glioma in adults.
Barthel FP, Johnson KC, Varn FS, Moskalik AD, Tanner G, Kocakavuk E, Anderson KJ, Abiola O, Aldape K, Alfaro KD, Alpar D, Amin SB, Ashley DM, Bandopadhayay P, Barnholtz-Sloan JS, Beroukhim R, Bock C, Brastianos PK, Brat DJ, Brodbelt AR, Bruns AF, Bulsara KR, Chakrabarty A, Chakravarti A, Chuang JH, Claus EB, Cochran EJ, Connelly J, Costello JF, Finocchiaro G, Fletcher MN, French PJ, Gan HK, Gilbert MR, Gould PV, Grimmer MR, Iavarone A, Ismail A, Jenkinson MD, Khasraw M, Kim H, Kouwenhoven MCM, LaViolette PS, Li M, Lichter P, Ligon KL, Lowman AK, Malta TM, Mazor T, McDonald KL, Molinaro AM, Nam DH, Nayyar N, Ng HK, Ngan CY, Niclou SP, Niers JM, Noushmehr H, Noorbakhsh J, Ormond DR, Park CK, Poisson LM, Rabadan R, Radlwimmer B, Rao G, Reifenberger G, Sa JK, Schuster M, Shaw BL, Short SC, Smitt PAS, Sloan AE, Smits M, Suzuki H, Tabatabai G, Van Meir EG, Watts C, Weller M, Wesseling P, Westerman BA, Widhalm G, Woehrer A, Yung WKA, Zadeh G, Huse JT, De Groot JF, Stead LF, Verhaak RGW; GLASS Consortium. Barthel FP, et al. Among authors: fletcher mn. Nature. 2019 Dec;576(7785):112-120. doi: 10.1038/s41586-019-1775-1. Epub 2019 Nov 20. Nature. 2019. PMID: 31748746 Free PMC article.
PFKFB4 interacts with FBXO28 to promote HIF-1α signaling in glioblastoma.
Phillips E, Balss J, Bethke F, Pusch S, Christen S, Hielscher T, Schnölzer M, Fletcher MNC, Habel A, Tessmer C, Brenner LM, Göttmann M, Capper D, Herold-Mende C, von Deimling A, Fendt SM, Goidts V. Phillips E, et al. Among authors: fletcher mnc. Oncogenesis. 2022 Sep 17;11(1):57. doi: 10.1038/s41389-022-00433-3. Oncogenesis. 2022. PMID: 36115843 Free PMC article.
A novel patient stratification strategy to enhance the therapeutic efficacy of dasatinib in glioblastoma.
Alhalabi OT, Fletcher MNC, Hielscher T, Kessler T, Lokumcu T, Baumgartner U, Wittmann E, Schlue S, Göttmann M, Rahman S, Hai L, Hansen-Palmus L, Puccio L, Nakano I, Herold-Mende C, Day BW, Wick W, Sahm F, Phillips E, Goidts V. Alhalabi OT, et al. Among authors: fletcher mnc. Neuro Oncol. 2022 Jan 5;24(1):39-51. doi: 10.1093/neuonc/noab158. Neuro Oncol. 2022. PMID: 34232320 Free PMC article.
Master regulators of FGFR2 signalling and breast cancer risk.
Fletcher MN, Castro MA, Wang X, de Santiago I, O'Reilly M, Chin SF, Rueda OM, Caldas C, Ponder BA, Markowetz F, Meyer KB. Fletcher MN, et al. Nat Commun. 2013;4:2464. doi: 10.1038/ncomms3464. Nat Commun. 2013. PMID: 24043118 Free PMC article.
Evolutionary Trajectories of IDHWT Glioblastomas Reveal a Common Path of Early Tumorigenesis Instigated Years ahead of Initial Diagnosis.
Körber V, Yang J, Barah P, Wu Y, Stichel D, Gu Z, Fletcher MNC, Jones D, Hentschel B, Lamszus K, Tonn JC, Schackert G, Sabel M, Felsberg J, Zacher A, Kaulich K, Hübschmann D, Herold-Mende C, von Deimling A, Weller M, Radlwimmer B, Schlesner M, Reifenberger G, Höfer T, Lichter P. Körber V, et al. Among authors: fletcher mnc. Cancer Cell. 2019 Apr 15;35(4):692-704.e12. doi: 10.1016/j.ccell.2019.02.007. Epub 2019 Mar 21. Cancer Cell. 2019. PMID: 30905762 Free article.
Genetic mapping of species differences via in vitro crosses in mouse embryonic stem cells.
Lazzarano S, Kučka M, Castro JPL, Naumann R, Medina P, Fletcher MNC, Wombacher R, Gribnau J, Hochepied T, Van Montagu M, Libert C, Chan YF. Lazzarano S, et al. Among authors: fletcher mnc. Proc Natl Acad Sci U S A. 2018 Apr 3;115(14):3680-3685. doi: 10.1073/pnas.1717474115. Epub 2018 Mar 21. Proc Natl Acad Sci U S A. 2018. PMID: 29563231 Free PMC article.
A Set of Cell Lines Derived from a Genetic Murine Glioblastoma Model Recapitulates Molecular and Morphological Characteristics of Human Tumors.
Costa B, Fletcher MNC, Boskovic P, Ivanova EL, Eisemann T, Lohr S, Bunse L, Löwer M, Burchard S, Korshunov A, Coltella N, Cusimano M, Naldini L, Liu HK, Platten M, Radlwimmer B, Angel P, Peterziel H. Costa B, et al. Among authors: fletcher mnc. Cancers (Basel). 2021 Jan 10;13(2):230. doi: 10.3390/cancers13020230. Cancers (Basel). 2021. PMID: 33435218 Free PMC article.
FGFR2 risk SNPs confer breast cancer risk by augmenting oestrogen responsiveness.
Campbell TM, Castro MAA, de Santiago I, Fletcher MNC, Halim S, Prathalingam R, Ponder BAJ, Meyer KB. Campbell TM, et al. Among authors: fletcher mnc. Carcinogenesis. 2016 Aug;37(8):741-750. doi: 10.1093/carcin/bgw065. Epub 2016 May 28. Carcinogenesis. 2016. PMID: 27236187 Free PMC article.