Bacteria were first detected in human tumors more than 100 years ago, but the characterization
of the tumor microbiome has remained challenging because of its low biomass. We …

Elevated postprandial blood glucose levels constitute a global epidemic and a major risk
factor for prediabetes and type II diabetes, but existing dietary methods for controlling them …

Human gut microbiome composition is shaped by multiple factors but the relative contribution
of host genetics remains elusive. Here we examine genotype and microbiome data from …

Non-caloric artificial sweeteners (NAS) are among the most widely used food additives
worldwide, regularly consumed by lean and obese individuals alike. NAS consumption is …

Despite extensive research, our understanding of the rules according to which cis-regulatory
sequences are converted into gene expression is limited. We devised a method for …

A variety of species of bacteria are known to colonize human tumours 1 , 2 , 3 , 4 , 5 , 6 , 7 , 8
, 9 , 10 – 11 , proliferate within them and modulate immune function, which ultimately affects …

The serum metabolome contains a plethora of biomarkers and causative agents of various
diseases, some of which are endogenously produced and some that have been taken up …

Metagenomic sequencing increased our understanding of the role of the microbiome in
health and disease, yet it only provides a snapshot of a highly dynamic ecosystem. Here, we …

INTRODUCTION The recruitment of the ribosome to a specific mRNA is a critical step in the
production of proteins in cells. In addition to a general recognition of the “cap” structure at the …

Complex diseases, such as coronary artery disease (CAD), are often multifactorial, caused
by multiple underlying pathological mechanisms. Here, to study the multifactorial nature of …