User profiles for Alexander P. Glaser

Alexander P. Glaser, MD

Division of Urology, NorthShore University HealthSystem
Verified email at northshore.org
Cited by 1144

Urinary tract infection and bacteriuria in pregnancy

AP Glaser, AJ Schaeffer - Urologic Clinics, 2015 - urologic.theclinics.com
Urinary tract infections (UTIs) during pregnancy may be classified as asymptomatic bacteriuria
(ASB), infections of the lower urinary tract (cystitis), or infections of the upper urinary tract (…

[HTML][HTML] A Carcinogen-induced mouse model recapitulates the molecular alterations of human muscle invasive bladder cancer

D Fantini, AP Glaser, KJ Rimar, Y Wang, M Schipma… - Oncogene, 2018 - nature.com
The N-butyl-N-(4-hydroxybutyl)-nitrosamine (BBN) mouse model is an attractive model
system of muscle-invasive bladder cancer (MIBC) as it recapitulates the histology of human …

The evolving genomic landscape of urothelial carcinoma

AP Glaser, D Fantini, A Shilatifard, EM Schaeffer… - Nature Reviews …, 2017 - nature.com
Survival of patients with urothelial carcinoma (including bladder cancer and upper tract
urothelial carcinoma) is limited by our current approaches to staging, surgery, and chemotherapy…

[HTML][HTML] APOBEC-mediated mutagenesis in urothelial carcinoma is associated with improved survival, mutations in DNA damage response genes, and immune …

AP Glaser, D Fantini, Y Wang, Y Yu, KJ Rimar… - Oncotarget, 2018 - ncbi.nlm.nih.gov
APOBEC enzymes are responsible for a mutation signature (TCW> T/G) implicated in a wide
variety of tumors. We explore the APOBEC mutational signature in bladder cancer and the …

[HTML][HTML] TNF is a potential therapeutic target to suppress prostatic inflammation and hyperplasia in autoimmune disease

…, J Petkewicz, P Talaty, BT Helfand, AP Glaser… - Nature …, 2022 - nature.com
Autoimmune (AI) diseases can affect many organs; however, the prostate has not been
considered to be a primary target of these systemic inflammatory processes. Here, we utilize …

Automated extraction of grade, stage, and quality information from transurethral resection of bladder tumor pathology reports using natural language processing

AP Glaser, BJ Jordan, J Cohen, A Desai… - JCO clinical cancer …, 2018 - ascopubs.org
Purpose Bladder cancer is initially diagnosed and staged with a transurethral resection of
bladder tumor (TURBT). Patient survival is dependent on appropriate sampling of layers of the …

The impact of prostate biopsy on urinary symptoms, erectile function, and anxiety

AP Glaser, K Novakovic, BT Helfand - Current urology reports, 2012 - Springer
Transrectal ultrasound-guided prostate needle biopsy (PB) is considered the gold standard
for the diagnosis of prostate cancer. Recently, lower urinary tract symptoms and erectile …

Prostate cancer diagnosis is associated with an increased risk of erectile dysfunction after prostate biopsy

BT Helfand, AP Glaser, K Rimar, S Zargaroff… - BJU …, 2013 - Wiley Online Library
What's known on the subject? and What does the study add? There have been several
studies that have suggested there may be a relationship between prostate biopsy and erectile …

Antibody targeting of B7-H4 enhances the immune response in urothelial carcinoma

JR Podojil, AP Glaser, D Baker, ET Courtois… - …, 2020 - Taylor & Francis
Patients with locally advanced and metastatic urothelial carcinoma have a low survival rate (median
15.7 months, 13.1–17.8), with only a 23% response rate to monotherapy treatment …

Surgeon scorecards improve muscle sampling on transurethral resection of bladder tumor and recurrence outcomes in patients with nonmuscle invasive bladder …

…, JE Cohen, OS Ko, BJ Jordan, AP Glaser… - The Journal of …, 2021 - auajournals.org
Purpose: The presence of detrusor muscle is essential for accurate staging of T1 cancers.
Detrusor muscle presence can be a quality indicator of transurethral resection of bladder …