User profiles for Andrew E. Pelling

Andrew E. Pelling

Pelling Lab for Augmented Biology
Verified email at pellinglab.net
Cited by 5116

Local Nanomechanical Motion of the Cell Wall of Saccharomyces cerevisiae

AE Pelling, S Sehati, EB Gralla, JS Valentine… - Science, 2004 - science.org
We demonstrate that the cell wall of living Saccharomyces cerevisiae (baker's yeast) exhibits
local temperature-dependent nanomechanical motion at characteristic frequencies. The …

[HTML][HTML] Moesin controls cortical rigidity, cell rounding, and spindle morphogenesis during mitosis

P Kunda, AE Pelling, T Liu, B Baum - Current biology, 2008 - cell.com
Background During mitosis, animal cells undergo a complex sequence of morphological
changes, from retraction of the cell margin and cell rounding at the onset of mitosis to axial …

Characterization of the interface between normal and transformed epithelial cells

…, M Kajita, C Zimmermann, AE Pelling, E Piddini… - Nature cell …, 2009 - nature.com
In most cancers, transformation begins in a single cell in an epithelial cell sheet 1 , 2 , 3 .
However, it is not known what happens at the interface between non-transformed (normal) and …

Investigating cell mechanics with atomic force microscopy

K Haase, AE Pelling - Journal of The Royal Society …, 2015 - royalsocietypublishing.org
Transmission of mechanical force is crucial for normal cell development and functioning.
However, the process of mechanotransduction cannot be studied in isolation from cell …

[HTML][HTML] Cellulose biomaterials for tissue engineering

RJ Hickey, AE Pelling - Frontiers in bioengineering and …, 2019 - frontiersin.org
In this review, we highlight the importance of nanostructure of cellulose-based biomaterials
to allow cellular adhesion, the contribution of nanostructure to macroscale mechanical …

[HTML][HTML] Biocompatibility of subcutaneously implanted plant-derived cellulose biomaterials

DJ Modulevsky, CM Cuerrier, AE Pelling - PloS one, 2016 - journals.plos.org
There is intense interest in developing novel biomaterials which support the invasion and
proliferation of living cells for potential applications in tissue engineering and regenerative …

[HTML][HTML] Apple derived cellulose scaffolds for 3D mammalian cell culture

…, C Lefebvre, K Haase, Z Al-Rekabi, AE Pelling - PloS one, 2014 - journals.plos.org
There are numerous approaches for producing natural and synthetic 3D scaffolds that
support the proliferation of mammalian cells. 3D scaffolds better represent the natural cellular …

Nanoscale visualization and characterization of Myxococcus xanthus cells with atomic force microscopy

AE Pelling, Y Li, W Shi… - Proceedings of the …, 2005 - National Acad Sciences
Multicellular microbial communities are the predominant form of existence for microorganisms
in nature. As one of the most primitive social organisms, Myxococcus xanthus has been an …

[HTML][HTML] Extracellular forces cause the nucleus to deform in a highly controlled anisotropic manner

…, S Hadjiantoniou, JL Harden, IS Skerjanc, AE Pelling - Scientific reports, 2016 - nature.com
Physical forces arising in the extra-cellular environment have a profound impact on cell fate
and gene regulation; however the underlying biophysical mechanisms that control this …

Force nanoscopy of cell mechanics and cell adhesion

YF Dufrêne, AE Pelling - Nanoscale, 2013 - pubs.rsc.org
Cells are constantly exposed to mechanical stimuli in their environment and have several
evolved mechanisms to sense and respond to these cues. It is becoming increasingly …