User profiles for Andrew H. Girgis

Andrew Girgis

University of Oxford
Verified email at oncology.ox.ac.uk
Cited by 1438

Multilevel whole-genome analysis reveals candidate biomarkers in clear cell renal cell carcinoma

AH Girgis, VV Iakovlev, B Beheshti, J Bayani, JA Squire… - Cancer research, 2012 - AACR
Renal cell carcinoma (RCC) is the most common neoplasm of the kidney. We conducted an
integrated analysis of copy number, gene expression (mRNA and miRNA), protein …

[HTML][HTML] The chromatin remodeling gene ARID1A is a new prognostic marker in clear cell renal cell carcinoma

Z Lichner, A Scorilas, NMA White, AH Girgis… - The American Journal of …, 2013 - Elsevier
Clear cell renal cell carcinoma (ccRCC) is the most common tumor of the adult kidney, with
an increasing rate of incidence. Recently, exome sequencing studies have revealed that the …

Integrated genomic characterization of the kallikrein gene locus in cancer

AH Girgis, A Bui, NM White, GM Yousef - Anticancer research, 2012 - ar.iiarjournals.org
Background: The kallikrein-related peptidases (KLKs) have been implicated in many types
of cancer, including prostate and ovarian. Materials and Methods: We performed a …

Clear Cell Renal Cell Carcinoma with Biallelic Inactivation of CDKN2A/B on 9p21 have Distinct Gene Expression Signature and are Associated with Poor Prognosis

AH Girgis - bioRxiv, 2017 - biorxiv.org
Purpose The clinical implications of biallelic inactivation of CDKN2A/B in clear cell renal cell
carcinoma (ccRCC) and relevant dysregulated biological pathways and gene signatures …

Abstract A34: BRCA1 and BRCA2 mutation spectrum across 5, 509 high-risk individuals identifies pathogenic variants associated with ethnicity, age of diagnosis, and …

AH Girgis, M Wang, A Fine, KR Zakoor… - Molecular Cancer …, 2016 - AACR
Hereditary Breast and Ovarian Cancer Sydrome (HBOC) accounts for approximately 5-10%
of breast and ovarian cancer cases and germline mutations of the BRCA1 and BRCA2 …

Kidney Cancer Genomics: Paving the Road to a New Paradigm of Personalized Medicine

GM Yousef, NMA White, AH Girgis - Cancer Genomics: Molecular …, 2012 - Springer
Renal cell carcinoma (RCC) is the most common neoplasm of the adult kidney. Unlike other
cancers, its incidence has risen in the past 20 years. The most common subtype of RCC is …

MG-126 Data sharing and variant classification consensus building in the canadian open genetics repository (COGR)

M Wang, S White, KR Zakoor, AH Girgis, MS Leboc… - 2015 - jmg.bmj.com
Background There is a critical need for collaborative measures between Canadian institutions
to better facilitate variant analysis and data sharing. Objectives The Canadian Open …

[HTML][HTML] Development and feasibility of a web-based decision aid for patients with ulcerative colitis: qualitative pilot study

…, SO Ruban, AJ Sechi, WSW Ng, JM Andrews… - Journal of medical …, 2021 - jmir.org
Background Shared decision making (SDM) is becoming an important part of ulcerative
colitis (UC) management because of the increasing complexity of available treatment choices …

[HTML][HTML] A web-based decision aid (myAID) to enhance quality of life, empowerment, decision making, and disease control for patients with ulcerative colitis: protocol …

…, AJ Sechi, J Descallar, JM Andrews… - JMIR Research …, 2020 - researchprotocols.org
Background: Patients with ulcerative colitis (UC) often face complex treatment decisions.
Although shared decision making (SDM) is considered important, tools to facilitate this are …

[HTML][HTML] Lactate dehydrogenase A is a potential prognostic marker in clear cell renal cell carcinoma

H Girgis, O Masui, NMA White, A Scorilas, F Rotondo… - Molecular cancer, 2014 - Springer
Background Over 90% of cancer-related deaths in clear cell renal cell carcinoma (RCC) are
caused by tumor relapse and metastasis. Thus, there is an urgent need for new molecular …