Large-scale population genomic surveys are essential to explore the phenotypic diversity of
natural populations. Here we report the whole-genome sequencing and phenotyping of …

Pangenomes provide access to an accurate representation of the genetic diversity of
species, both in terms of sequence polymorphisms and structural variants (SVs). Here we …

The Pictet−Spengler reaction, which yields either a β-carboline or a tetrahydroquinoline product
from an aromatic amine and an aldehyde, is widely utilized in plant alkaloid biosynthesis…

Aims/hypothesis Pancreatic islet beta cell failure causes type 2 diabetes in humans. To
identify transcriptomic changes in type 2 diabetic islets, the Innovative Medicines Initiative for …

Background: Oxford Nanopore Technologies Ltd (Oxford, UK) have recently commercialized
MinION, a small single-molecule nanopore sequencer, that offers the possibility of …

Background The Red proteins of lambda phage mediate probably the simplest and most
efficient homologous recombination reactions yet described. However the mechanism of …

Understanding the molecular basis of how reproductive isolation evolves between individuals
from the same species offers valuable insight into patterns of genetic differentiation as well …

Polyploidization is an important process in the evolution of eukaryotic genomes, but
ensuing molecular mechanisms remain to be clarified. Autopolyploidization or whole-genome …

Mitochondria are important organelles that harbor their own genomes encoding a key set of
proteins that ensure respiration and provide the eukaryotic cell with energy. Recent …

Production of leavened bread dates to the second millennium BCE. Since then, the art of
bread making has developed, yet the evolution of bread-associated microbial species remains …