Temperate bacteriophages play an important role in the pathogenicity of Staphylococcus
aureus, for instance, by mediating the horizontal gene transfer of virulence factors. Here we …

Background and Purpose— Recent studies have attributed the increased infection
vulnerability of patients with stroke to stroke-induced immunosuppression. We have therefore …

A clinically important adverse drug reaction, heparin-induced thrombocytopenia (HIT), is
induced by antibodies specific for complexes of the chemokine platelet factor 4 (PF4) and the …

The outcome of encounters between Staphylococcus (S.) aureus and its human host ranges
from life-threatening infection through allergic reactions to symptom-free colonization. The …

Vaccination using the adenoviral vector COVID-19 vaccine ChAdOx1 nCoV-19 (AstraZeneca)
has been associated with rare vaccine-induced immune thrombotic thrombocytopenia (…

The Study of Health in Pomerania (SHIP) comprises the two independent cohorts SHIP-START
(recruited between 1997 and 2001) and SHIP-TREND (recruited between 2008 to 2012), …

The two-component system SaeRS consisting of the histidin kinase SaeS and the response
regulator SaeR is known to act on virulence gene expression in Staphylococcus aureus. In …

Background & Aims Pancreatitis starts with primarily sterile local inflammation that induces
systemic inflammatory response syndrome, followed by compensatory anti-inflammatory …

Sequencing of at least 13 Staphylococcus aureus isolates has shown that genomic plasticity
impacts significantly on the repertoire of virulence factors. However, genome sequencing …

A subset of B cells expressing the CD5 marker, a 67 KD molecule, has been implicated in the
pathogenesis of autoimmune disease. To study the immunoglobulin repertoire of CD5 + B …