About three quarter of all eukaryotic DNA is wrapped around protein cylinders, forming
nucleosomes. Even though the histone proteins that make up the core of nucleosomes are highly …

Due to their specificity, efficiency, and ease of programming, CRISPR-associated nucleases
are popular tools for genome editing. On the genomic scale, these nucleases still show …

In stationary-phase Escherichia coli, Dps (DNA-binding protein from starved cells) is the
most abundant protein component of the nucleoid. Dps compacts DNA into a dense complex …

Eukaryotic DNA is strongly bent inside fundamental packaging units: the nucleosomes. It is
known that their positions are strongly influenced by the mechanical properties of the …

The S. pyogenes (Sp) Cas9 endonuclease is an important gene-editing tool. SpCas9 is
directed to target sites based on complementarity to a complexed single-guide RNA (sgRNA). …

Nucleosomes, DNA spools with a protein core, engage about three-quarters of eukaryotic
DNA and play a critical role in chromosomal processes, ranging from gene regulation, …

Pausing by bacterial RNA polymerase (RNAp) is vital in the recruitment of regulatory factors,
RNA folding, and coupled translation. While backtracking and intra-structural isomerization …

We study the conformations of a semiflexible chain, confined in nano-scaled spherical
cavities, under two distinct processes of confinement. Radial contraction and packaging are …

Future energy infrastructures are expected to be smart, with the application of energy storage
and demand-side management strategies. To size the energy storage and assess the …

Pausing by RNA polymerase (RNAp) facilitates the recruitment of regulatory factors, RNA
folding, and other related processes. While backtracking and intra-structural isomerization …