User profiles for Christine S. Hansen
 | Christine Søholm HansenStatens Serum Institut Verified email at ssi.dk Cited by 16669 |
Discovery of the first genome-wide significant risk loci for attention deficit/hyperactivity disorder
…, J Bybjerg-Grauholm, M Bækvad-Hansen… - Nature …, 2019 - nature.com
Attention deficit/hyperactivity disorder (ADHD) is a highly heritable childhood behavioral
disorder affecting 5% of children and 2.5% of adults. Common genetic variants contribute …
disorder affecting 5% of children and 2.5% of adults. Common genetic variants contribute …
Identification of common genetic risk variants for autism spectrum disorder
…, S Djurovic, AL Dumont, JI Goldstein, CS Hansen… - Nature …, 2019 - nature.com
Autism spectrum disorder (ASD) is a highly heritable and heterogeneous group of
neurodevelopmental phenotypes diagnosed in more than 1% of children. Common genetic variants …
neurodevelopmental phenotypes diagnosed in more than 1% of children. Common genetic variants …
[PDF][PDF] Genomic relationships, novel loci, and pleiotropic mechanisms across eight psychiatric disorders
Genetic influences on psychiatric disorders transcend diagnostic boundaries, suggesting
substantial pleiotropy of contributing loci. However, the nature and mechanisms of these …
substantial pleiotropy of contributing loci. However, the nature and mechanisms of these …
[HTML][HTML] An epigenetic clock for gestational age at birth based on blood methylation data
Background Gestational age is often used as a proxy for developmental maturity by clinicians
and researchers alike. DNA methylation has previously been shown to be associated with …
and researchers alike. DNA methylation has previously been shown to be associated with …
Common risk variants identified in autism spectrum disorder
…, S Djurovic, A Dumont, J Goldstein, CS Hansen… - biorxiv, 2017 - biorxiv.org
Autism spectrum disorder (ASD) is a highly heritable and heterogeneous group of
neurodevelopmental phenotypes diagnosed in more than 1% of children. Common genetic variants …
neurodevelopmental phenotypes diagnosed in more than 1% of children. Common genetic variants …
Gene expression profiling of archived dried blood spot samples from the Danish Neonatal Screening Biobank
A large part of the human genome is transcribed into various forms of RNA, and the global
gene expression profile (GEP) has been studied for several years using technology such as …
gene expression profile (GEP) has been studied for several years using technology such as …
[HTML][HTML] Schizophrenia-associated mt-DNA SNPs exhibit highly variable haplogroup affiliation and nuclear ancestry: Bi-genomic dependence raises major concerns …
Mitochondria play a significant role in human diseases. However, disease associations with
mitochondrial DNA (mtDNA) SNPs have proven difficult to replicate. An analysis of eight …
mitochondrial DNA (mtDNA) SNPs have proven difficult to replicate. An analysis of eight …
[HTML][HTML] Evaluation of whole genome amplified DNA to decrease material expenditure and increase quality
M Bækvad-Hansen, J Bybjerg-Grauholm… - Molecular Genetics and …, 2017 - Elsevier
Aim The overall aim of this study is to evaluate whole genome amplification of DNA extracted
from dried blood spot samples. We wish to explore ways of optimizing the amplification …
from dried blood spot samples. We wish to explore ways of optimizing the amplification …
[HTML][HTML] Genetic regulation of spermine oxidase activity and cancer risk: a Mendelian randomization study
Spermine oxidase (SMOX) catalyzes the oxidation of spermine to spermidine. Observational
studies have reported SMOX as a source of reactive oxygen species associated with cancer…
studies have reported SMOX as a source of reactive oxygen species associated with cancer…
Idiopathic early ovarian aging: is there a relation with premenopausal accelerated biological aging in young women with diminished response to ART?
Purpose To evaluate whether young women with idiopathic early ovarian aging, as defined
by producing fewer oocytes than expected for a given age over multiple in vitro fertilization (…
by producing fewer oocytes than expected for a given age over multiple in vitro fertilization (…