User profiles for Chun-Chieh Fan
 | Chun Chieh FanLaureate Institute for Brain Research Verified email at laureateinstitute.org Cited by 8585 |
Genome-wide association study identifies 30 loci associated with bipolar disorder
…, A Dumont, T Elvsåshagen, V Escott-Price, CC Fan… - Nature …, 2019 - nature.com
Bipolar disorder is a highly heritable psychiatric disorder. We performed a genome-wide
association study (GWAS) including 20,352 cases and 31,358 controls of European descent, …
association study (GWAS) including 20,352 cases and 31,358 controls of European descent, …
The genetic architecture of the human cerebral cortex
…, K Dohm, S Ehrlich, HR Engelbrecht, S Erk, CC Fan… - Science, 2020 - science.org
INTRODUCTION The cerebral cortex underlies our complex cognitive capabilities.
Variations in human cortical surface area and thickness are associated with neurological, …
Variations in human cortical surface area and thickness are associated with neurological, …
Exploring comorbidity within mental disorders among a Danish national population
Importance Individuals with mental disorders often develop comorbidity over time. Past
studies of comorbidity have often restricted analyses to a subset of disorders and few studies …
studies of comorbidity have often restricted analyses to a subset of disorders and few studies …
[PDF][PDF] Genomic dissection of bipolar disorder and schizophrenia, including 28 subphenotypes
…, V Escott-Price, T Esko, L Essioux, B Etain, CC Fan… - Cell, 2018 - cell.com
Schizophrenia and bipolar disorder are two distinct diagnoses that share symptomology.
Understanding the genetic factors contributing to the shared and disorder-specific symptoms …
Understanding the genetic factors contributing to the shared and disorder-specific symptoms …
[HTML][HTML] Genetic assessment of age-associated Alzheimer disease risk: development and validation of a polygenic hazard score
Background Identifying individuals at risk for developing Alzheimer disease (AD) is of utmost
importance. Although genetic studies have identified AD-associated SNPs in APOE and …
importance. Although genetic studies have identified AD-associated SNPs in APOE and …
Genome-wide analyses for personality traits identify six genomic loci and show correlations with psychiatric disorders
Personality is influenced by genetic and environmental factors 1 and associated with mental
health. However, the underlying genetic determinants are largely unknown. We identified …
health. However, the underlying genetic determinants are largely unknown. We identified …
RICOPILI: rapid imputation for COnsortias PIpeLIne
Genome-wide association study (GWAS) analyses, at sufficient sample sizes and power,
have successfully revealed biological insights for several complex traits. RICOPILI, an open-…
have successfully revealed biological insights for several complex traits. RICOPILI, an open-…
[HTML][HTML] Meaningful associations in the adolescent brain cognitive development study
The Adolescent Brain Cognitive Development (ABCD) Study is the largest single-cohort
prospective longitudinal study of neurodevelopment and children's health in the United States. A …
prospective longitudinal study of neurodevelopment and children's health in the United States. A …
[HTML][HTML] Bivariate causal mixture model quantifies polygenic overlap between complex traits beyond genetic correlation
Accumulating evidence from genome wide association studies (GWAS) suggests an
abundance of shared genetic influences among complex human traits and disorders, such as …
abundance of shared genetic influences among complex human traits and disorders, such as …
[HTML][HTML] Understanding the genetic determinants of the brain with MOSTest
Regional brain morphology has a complex genetic architecture, consisting of many common
polymorphisms with small individual effects. This has proven challenging for genome-wide …
polymorphisms with small individual effects. This has proven challenging for genome-wide …