Site-specific recombinases are potent tools to regulate gene expression. In particular, the Cre
(cyclization recombination) and FLP (flipase) enzymes are widely used to either activate or …

The nuclear envelope, which protects and organizes the genome, is dismantled during
mitosis. In the Caenorhabditis elegans zygote, nuclear envelope breakdown (NEBD) of the …

Nucleoporins are the constituents of nuclear pore complexes (NPCs) and are essential
regulators of nucleocytoplasmic transport, gene expression and genome stability. The …

Background Laminopathies are diseases characterized by defects in nuclear envelope
structure. A well-known example is Emery-Dreifuss muscular dystrophy, which is caused by …

Nuclear pore complexes consist of several subcomplexes. The NUP107 complex is important
for nucleocytoplasmic transport, nuclear envelope assembly, and kinetochore function. …

Nuclear pore complexes (NPCs) are gateways for transport between the nucleus and
cytoplasm of eukaryotic cells and play crucial roles in regulation of gene expression. NPCs are …

SWI/SNF ATP-dependent chromatin-remodeling complexes have been related to several
cellular processes such as transcription, regulation of chromosomal stability, and DNA repair. …

Control of gene expression in specific tissues and/or at certain stages of development allows
the study and manipulation of gene function with high precision. Site-specific genome …

Figure 1 Spatiotemporal control of genome recombination through combined FLP and cGAL
activities.(A) Reporter construct used to evaluate FLP recombinase activity. In the absence …

Purpose ‐ Bizkaia, an area of just over one million inhabitants, is the setting, through the
xertatu project, of an experience for fostering corporate social responsibility (CSR). This …