User profiles for Daniel H Stones

Daniel H. Stones

Senior Lecturer in Biosciences, University of Gloucestershire
Verified email at glos.ac.uk
Cited by 604

[HTML][HTML] Fatal attraction: how bacterial adhesins affect host signaling and what we can learn from them

DH Stones, AM Krachler - International journal of molecular sciences, 2015 - mdpi.com
The ability of bacterial species to colonize and infect host organisms is critically dependent
upon their capacity to adhere to cellular surfaces of the host. Adherence to cell surfaces is …

[PDF][PDF] Luminal iron levels govern intestinal tumorigenesis after Apc loss in vivo

…, E McGhee, K Anderson, SJ Ford, DH Stones… - Cell reports, 2012 - cell.com
It is clear from epidemiological studies that excess iron is associated with increased risk of
colorectal cancer; however, questions regarding the mechanism of how iron increases cancer …

[HTML][HTML] The antigenic identity of human class I MHC phosphopeptides is critically dependent upon phosphorylation status

F Mohammed, DH Stones, AL Zarling, CR Willcox… - Oncotarget, 2017 - ncbi.nlm.nih.gov
Dysregulated post-translational modification provides a source of altered self-antigens that
can stimulate immune responses in autoimmunity, inflammation, and cancer. In recent years, …

Zebrafish (Danio rerio) as a vertebrate model host to study colonization, pathogenesis, and transmission of foodborne Escherichia coli O157

DH Stones, AGJ Fehr, L Thompson, J Rocha… - MSphere, 2017 - Am Soc Microbiol
Foodborne infections with enterohemorrhagic Escherichia coli (EHEC) are a major cause of
diarrheal illness in humans and can lead to severe complications such as hemolytic uremic …

[HTML][HTML] Targeting bacterial adherence inhibits multidrug-resistant Pseudomonas aeruginosa infection following burn injury

RM Huebinger, DH Stones, M de Souza Santos… - Scientific reports, 2016 - nature.com
Classical antimicrobial drugs target proliferation and therefore place microbes under extreme
selective pressure to evolve resistance. Alternative drugs that target bacterial virulence …

[HTML][HTML] Multivalent adhesion molecule 7 clusters act as signaling platform for host cellular GTPase activation and facilitate epithelial barrier dysfunction

J Lim, DH Stones, CA Hawley, CA Watson… - PLoS …, 2014 - journals.plos.org
Vibrio parahaemolyticus is an emerging bacterial pathogen which colonizes the
gastrointestinal tract and can cause severe enteritis and bacteraemia. During infection, V. …

[HTML][HTML] 3-Sulfogalactosyl–dependent adhesion of Escherichia coli HS multivalent adhesion molecule is attenuated by sulfatase activity

F Al-Saedi, DP Vaz, DH Stones, AM Krachler - Journal of Biological …, 2017 - ASBMB
Bacterial adhesion to host receptors is an early and essential step in bacterial colonization,
and the nature of adhesin–receptor interactions determines bacterial localization and thus …

Against the tide: the role of bacterial adhesion in host colonization

DH Stones, AM Krachler - Biochemical Society Transactions, 2016 - portlandpress.com
… The topic was more comprehensively reviewed by Stones and Krachler [57]. … The gastric
pathogen and carcinogen H. pylori also co-opt integrin signaling for delivery and activation of …

Biomimetic materials to characterize bacteria-host interactions

DH Stones, F Al-Saedi, D Vaz, N Perez-Soto… - JoVE (Journal of …, 2015 - jove.com
Bacterial attachment to host cells is one of the earliest events during bacterial colonization
of host tissues and thus a key step during infection. The biochemical and functional …

Wheel thermal damage limits

DH Stone, GF Carpenter - Proceedings of IEEE/ASME Joint …, 1994 - ieeexplore.ieee.org
A series of dynamometer tests were conducted to determine the limiting power required to
produce wheel thermal damage, or the neutralization of the as-manufactured rim …