the primary analysis is unfortunately common. In early phase studies in a pandemic, little is
known for certain, and it seems biologically plausible that treating patients earlier could be …

In efforts to synthesize a clear understanding of SARS-CoV-2 (severe acute respiratory
syndrome coronavirus 2) protective immunity, antibody analysis has been paralleled by T cell …

Vaccine candidates based on spike, the glycoprotein that is essential for host cell entry by
severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), were being designed within …

Most vaccine platforms use a two-dose prime-boost approach to generate an immune
response against the virus S1 spike protein, the titres of which correlate with functional virus …

As SARS-CoV-2 vaccines are deployed worldwide, a comparative evaluation is important to
underpin decision-making. We here report a systematic literature review and meta-analysis …

Background There is growing concern about individuals reported to suffer repeat COVID-19
disease episodes, these in a small number of cases characterised as de novo infections …

The Omicron, or Pango lineage B.1.1.529, variant of severe acute respiratory syndrome
coronavirus 2 (SARS-CoV-2) carries multiple spike mutations with high transmissibility and …

Individuals with potential exposure to severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)
do not necessarily develop PCR or antibody positivity, suggesting that some …

Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) vaccine rollout has coincided
with the spread of variants of concern. We investigated whether single-dose vaccination, …

Long COVID is the patient-coined term for the disease entity whereby persistent symptoms
ensue in a significant proportion of those who have had COVID-19, whether asymptomatic, …