Growth differentiation factor 15 (GDF15) is a member of the TGFβ superfamily whose
expression is increased in response to cellular stress and disease as well as by metformin. …

Although successful in identifying new cataract-linked genes, the previous version of the
database iSyTE (integrated Systems Tool for Eye gene discovery) was based on expression …

Background Atherosclerotic plaque ruptures, triggered by blood flow–associated biomechanical
forces, cause most myocardial infarctions and strokes. Objectives This study aims to …

Cataracts cause vision loss and blindness by impairing the ability of the ocular lens to focus
light onto the retina. Various cataract risk factors have been identified, including drug …

… dr Đorđe Đorđević …

Motivation: Genome-wide mapping of chromatin states is essential for defining regulatory
elements and inferring their activities in eukaryotic genomes. A number of hidden Markov …

Featured Application This work illustrates that world-class architecture can be coupled with
building integrated (BIPV) or building applied (BAPV) photovoltaic (PV) technologies, which …

Proprotein convertase subtilisin/kexins (PCSKs) constitute a family of nine related proteases:
PCSK1-7, MBTPS1, and PCSK9. Apart from PCSK9, little is known about PCSKs in …

Gene regulatory networks (GRNs) play a central role in systems biology, especially in the
study of mammalian organ development. One key question remains largely unanswered: Is it …

Motivation Gene set analysis is a powerful tool for determining whether an experimentally
derived set of genes is statistically significantly enriched for genes in other pre-defined gene …