… Mice were euthanized by CO 2 inhalation. The aorta and first-order mesenteric artery branches
were … were performed per mouse, and the last 10 readings were recorded and averaged. …

Neutrophils are short-lived blood cells that play a critical role in host defense against infections.
To better comprehend neutrophil functions and their regulation, we provide a complete …

… were performed according to established procedures and when PCR fragments were involved
their sequences were … DNA binding domain and activation domain fusion proteins were …

… mice were euthanized and fetuses were obtained by C-section. Before tissue harvest, adult
animals were killed … All experiments were performed according to local ethical guidelines and …

… Assays were stopped with Laemmli sample buffer and … were grown and treated with S-nitroso-L-cysteine
as described.15, 16 For preparing cell protein extracts, confluent cells were …

Keratins K8 and K18 are the major components of the intermediate-filament cytoskeleton of
simple epithelia. Increased levels of these keratins have been correlated with various tumor …

Specificity of signaling kinases and phosphatases toward their targets is usually mediated
by docking interactions with substrates and regulatory proteins. Here, we characterize the …

The nuclear factor of activated T cells (NFAT) family of transcription factors regulates the
transcription of cytokine genes and other genes involved in the regulation and function of the …

Hematopoiesis is one of the best characterized biological systems but the connection
between chromatin changes and lineage differentiation is not yet well understood. We have …

Keratin 8 is a type II intermediate filament protein found in simple epithelia. We have introduced
a 12 kb DNA fragment of the human K8 locus into the germ line of mice. The transgene, …