We sequenced the genomes of a ∼7,000-year-old farmer from Germany and eight ∼8,000-year-old
hunter-gatherers from Luxembourg and Sweden. We analysed these and other …

Founder analysis is a method for analysis of nonrecombining DNA sequence data, with the
aim of identification and dating of migrations into new territory. The method picks out founder …

We explored the phylogeography of human Y-chromosomal haplogroup E3b by analyzing
3,401 individuals from five continents. Our data refine the phylogeny of the entire haplogroup, …

Over the past few years, studies of DNA isolated from human fossils and archaeological
remains have generated considerable novel insight into the history of our species. Several …

Phenotypic and biochemical categorization of humans with detrimental variants can provide
valuable information on gene function. We illustrate this with the identification of two …

Clinical data suggest that brain catecholamines and serotonin are deficient in phenylketonuria
(PKU), an inherited metabolic disorder that causes severe mental retardation and …

The Mediterranean region has been characterised by a number of pre‐historical and historical
demographic events whose legacy on the current genetic landscape is still a matter of …

The incorporation of reference DNA is crucial to the validation of any DNA typing protocol.
This paper aims to provide a panel of reference DNAs for actual forensic profiling strategies, ie …

The presence or absence of genetic heterogeneity in Sicily has long been debated.
Through the analysis of the variation of Y-chromosome lineages, using the combination of …

An increasing number of developmental and epileptic encephalopathies have been correlated
with variants of ion channel genes, and in particular of potassium channels genes, such …