User profiles for Guillermo Rodrigo

Guillermo Rodrigo

I2SYSBIO (CSIC - UV)
Verified email at csic.es
Cited by 2015

De novo automated design of small RNA circuits for engineering synthetic riboregulation in living cells

G Rodrigo, TE Landrain… - Proceedings of the …, 2012 - National Acad Sciences
A grand challenge in synthetic biology is to use our current knowledge of RNA science to
perform the automatic engineering of completely synthetic sequences encoding functional …

Diagnostics of infections produced by the plant viruses TMV, TEV, and PVX with CRISPR-Cas12 and CRISPR-Cas13

…, G Gómez, A Carbonell, JA Daròs, G Rodrigo - ACS synthetic …, 2022 - ACS Publications
Viral infections in plants threaten food security. Thus, simple and effective methods for virus
detection are required to adopt early measures that can prevent virus spread. However, …

Towards an integrated molecular model of plant–virus interactions

SF Elena, G Rodrigo - Current Opinion in Virology, 2012 - Elsevier
The application in recent years of network theory methods to the study of host–virus interactions
is providing a new perspective to the way viruses manipulate the host to promote their …

[HTML][HTML] Programmable regulation of translation by harnessing the CRISPR-Cas13 system

…, R Márquez-Costa, G Rodrigo - Chemical …, 2023 - pubs.rsc.org
The ability to control protein expression at both the transcriptional and post-transcriptional
levels is instrumental for the cell to integrate multiple molecular signals and then reach high …

Dynamic signal processing by ribozyme-mediated RNA circuits to control gene expression

S Shen, G Rodrigo, S Prakash, E Majer… - Nucleic acids …, 2015 - academic.oup.com
Organisms have different circuitries that allow converting signal molecule levels to changes
in gene expression. An important challenge in synthetic biology involves the de novo design …

[HTML][HTML] Gene regulation by a protein translation factor at the single-cell level

…, R Montagud-Martínez, G Rodrigo - PLOS Computational …, 2022 - journals.plos.org
Gene expression is inherently stochastic and pervasively regulated. While substantial work
combining theory and experiments has been carried out to study how noise propagates …

DESHARKY: automatic design of metabolic pathways for optimal cell growth

G Rodrigo, J Carrera, KJ Prather, A Jaramillo - Bioinformatics, 2008 - academic.oup.com
Motivation: The biological solution for synthesis or remediation of organic compounds using
living organisms, particularly bacteria and yeast, has been promoted because of the cost …

Identification, introgression, and validation of fruit volatile QTLs from a red-fruited wild tomato species

…, G López-Casado, G Rodrigo… - Journal of …, 2017 - academic.oup.com
Volatile organic compounds (VOCs) are major determinants of fruit flavor, a primary objective
in tomato breeding. A recombinant inbred line (RIL) population consisting of 169 lines …

[PDF][PDF] Abscisic acid connects phytohormone signaling with RNA metabolic pathways and promotes an antiviral response that is evaded by a self-controlled RNA virus

…, DH Fresno, K Fatyol, S Munne-Bosch, G Rodrigo… - Plant …, 2020 - cell.com
A complex network of cellular receptors, RNA targeting pathways, and small-molecule
signaling provides robust plant immunity and tolerance to viruses. To maximize their fitness, …

[HTML][HTML] A Meta-Analysis Reveals the Commonalities and Differences in Arabidopsis thaliana Response to Different Viral Pathogens

G Rodrigo, J Carrera, V Ruiz-Ferrer, FJ del Toro… - PLoS …, 2012 - journals.plos.org
Understanding the mechanisms by which plants trigger host defenses in response to
viruses has been a challenging problem owing to the multiplicity of factors and complexity of …