[HTML][HTML] Molecular evolution of GPCRs: Kisspeptin/kisspeptin receptors

J Pasquier, N Kamech, AG Lafont… - Journal of Molecular …, 2014 - Soc Endocrinology
Kiss gene transcription, translation, and post-translational processing. CDS, coding
sequence; SP, signal peptide. The minimal bioactive sequence, composed by ten amino …

[HTML][HTML] The spotted gar genome illuminates vertebrate evolution and facilitates human-teleost comparisons

…, JJ Smith, K Kawasaki, T Manousaki, J Pasquier… - Nature …, 2016 - nature.com
To connect human biology to fish biomedical models, we sequenced the genome of spotted
gar (Lepisosteus oculatus), whose lineage diverged from teleosts before teleost genome …

[HTML][HTML] Comparative evolutionary histories of kisspeptins and kisspeptin receptors in vertebrates reveal both parallel and divergent features

J Pasquier, AG Lafont, H Tostivint, H Vaudry… - Frontiers in …, 2012 - frontiersin.org
During the past decade, the kisspeptin system has been identified in various vertebrates,
leading to the discovery of multiple genes encoding both peptides (Kiss) and receptors (Kissr). …

[HTML][HTML] Multiple kisspeptin receptors in early osteichthyans provide new insights into the evolution of this receptor family

J Pasquier, AG Lafont, SR Jeng, M Morini, R Dirks… - PLoS …, 2012 - journals.plos.org
Deorphanization of GPR54 receptor a decade ago led to the characterization of the kisspeptin
receptor (Kissr) in mammals and the discovery of its major role in the brain control of …

[HTML][HTML] Gene evolution and gene expression after whole genome duplication in fish: the PhyloFish database

J Pasquier, C Cabau, T Nguyen, E Jouanno, D Severac… - BMC genomics, 2016 - Springer
With more than 30,000 species, ray-finned fish represent approximately half of vertebrates.
The evolution of ray-finned fish was impacted by several whole genome duplication (WGD) …

[HTML][HTML] Looking for the bird Kiss: evolutionary scenario in sauropsids

J Pasquier, AG Lafont, K Rousseau, B Quérat… - BMC evolutionary …, 2014 - Springer
Background The neuropeptide Kiss and its receptor KissR are key-actors in the brain control
of reproduction in mammals, where they are responsible for the stimulation of the activity of …

[HTML][HTML] Duplicated leptin receptors in two species of eel bring new insights into the evolution of the leptin system in vertebrates

M Morini, J Pasquier, R Dirks, G van den Thillart… - PLoS …, 2015 - journals.plos.org
Since its discovery in mammals as a key-hormone in reproduction and metabolism, leptin has
been identified in an increasing number of tetrapods and teleosts. Tetrapods possess only …

First evidence for a direct inhibitory effect of kisspeptins on LH expression in the eel, Anguilla anguilla

J Pasquier, AG Lafont, J Leprince, H Vaudry… - General and …, 2011 - Elsevier
The kisspeptin system has emerged as one of the main puberty gatekeepers among vertebrates.
The European eel (Anguilla anguilla) is a remarkable model due to its phylogenetical …

Foxl2 and its relatives are evolutionary conserved players in gonadal sex differentiation

S Bertho, J Pasquier, Q Pan, G Le Trionnaire… - Sexual …, 2016 - karger.com
Foxl2 is a member of the large family of Forkhead Box (Fox) domain transcription factors. It
emerged during the last 15 years as a key player in ovarian differentiation and oogenesis in …

[HTML][HTML] Prevalence of Plasmodium spp. in illegal gold miners in French Guiana in 2015: a hidden but critical malaria reservoir

M Douine, L Musset, F Corlin, S Pelleau, J Pasquier… - Malaria journal, 2016 - Springer
Background Malaria is endemic in French Guiana, an overseas territory of France on the
Guiana Shield. Since 2005, notified malaria cases are decreasing. However, new data show …