[HTML][HTML] Molecular evolution of GPCRs: Kisspeptin/kisspeptin receptors
J Pasquier, N Kamech, AG Lafont… - Journal of Molecular …, 2014 - Soc Endocrinology
Kiss gene transcription, translation, and post-translational processing. CDS, coding
sequence; SP, signal peptide. The minimal bioactive sequence, composed by ten amino …
sequence; SP, signal peptide. The minimal bioactive sequence, composed by ten amino …
[HTML][HTML] The spotted gar genome illuminates vertebrate evolution and facilitates human-teleost comparisons
…, JJ Smith, K Kawasaki, T Manousaki, J Pasquier… - Nature …, 2016 - nature.com
To connect human biology to fish biomedical models, we sequenced the genome of spotted
gar (Lepisosteus oculatus), whose lineage diverged from teleosts before teleost genome …
gar (Lepisosteus oculatus), whose lineage diverged from teleosts before teleost genome …
[HTML][HTML] Comparative evolutionary histories of kisspeptins and kisspeptin receptors in vertebrates reveal both parallel and divergent features
J Pasquier, AG Lafont, H Tostivint, H Vaudry… - Frontiers in …, 2012 - frontiersin.org
During the past decade, the kisspeptin system has been identified in various vertebrates,
leading to the discovery of multiple genes encoding both peptides (Kiss) and receptors (Kissr). …
leading to the discovery of multiple genes encoding both peptides (Kiss) and receptors (Kissr). …
[HTML][HTML] Multiple kisspeptin receptors in early osteichthyans provide new insights into the evolution of this receptor family
Deorphanization of GPR54 receptor a decade ago led to the characterization of the kisspeptin
receptor (Kissr) in mammals and the discovery of its major role in the brain control of …
receptor (Kissr) in mammals and the discovery of its major role in the brain control of …
[HTML][HTML] Gene evolution and gene expression after whole genome duplication in fish: the PhyloFish database
J Pasquier, C Cabau, T Nguyen, E Jouanno, D Severac… - BMC genomics, 2016 - Springer
With more than 30,000 species, ray-finned fish represent approximately half of vertebrates.
The evolution of ray-finned fish was impacted by several whole genome duplication (WGD) …
The evolution of ray-finned fish was impacted by several whole genome duplication (WGD) …
[HTML][HTML] Looking for the bird Kiss: evolutionary scenario in sauropsids
J Pasquier, AG Lafont, K Rousseau, B Quérat… - BMC evolutionary …, 2014 - Springer
Background The neuropeptide Kiss and its receptor KissR are key-actors in the brain control
of reproduction in mammals, where they are responsible for the stimulation of the activity of …
of reproduction in mammals, where they are responsible for the stimulation of the activity of …
[HTML][HTML] Duplicated leptin receptors in two species of eel bring new insights into the evolution of the leptin system in vertebrates
Since its discovery in mammals as a key-hormone in reproduction and metabolism, leptin has
been identified in an increasing number of tetrapods and teleosts. Tetrapods possess only …
been identified in an increasing number of tetrapods and teleosts. Tetrapods possess only …
First evidence for a direct inhibitory effect of kisspeptins on LH expression in the eel, Anguilla anguilla
J Pasquier, AG Lafont, J Leprince, H Vaudry… - General and …, 2011 - Elsevier
The kisspeptin system has emerged as one of the main puberty gatekeepers among vertebrates.
The European eel (Anguilla anguilla) is a remarkable model due to its phylogenetical …
The European eel (Anguilla anguilla) is a remarkable model due to its phylogenetical …
Foxl2 and its relatives are evolutionary conserved players in gonadal sex differentiation
S Bertho, J Pasquier, Q Pan, G Le Trionnaire… - Sexual …, 2016 - karger.com
Foxl2 is a member of the large family of Forkhead Box (Fox) domain transcription factors. It
emerged during the last 15 years as a key player in ovarian differentiation and oogenesis in …
emerged during the last 15 years as a key player in ovarian differentiation and oogenesis in …
[HTML][HTML] Prevalence of Plasmodium spp. in illegal gold miners in French Guiana in 2015: a hidden but critical malaria reservoir
Background Malaria is endemic in French Guiana, an overseas territory of France on the
Guiana Shield. Since 2005, notified malaria cases are decreasing. However, new data show …
Guiana Shield. Since 2005, notified malaria cases are decreasing. However, new data show …