User profiles for Jéróme Bonnet
Jerome BonnetGroup Leader, Centre de Biochimie Structurale, Montpellier, France Verified email at cbs.cnrs.fr Cited by 2554 |
Amplifying genetic logic gates
Organisms must process information encoded via developmental and environmental signals
to survive and reproduce. Researchers have also engineered synthetic genetic logic to …
to survive and reproduce. Researchers have also engineered synthetic genetic logic to …
[HTML][HTML] Polycomb-dependent regulatory contacts between distant Hox loci in Drosophila
In Drosophila melanogaster, Hox genes are organized in an anterior and a posterior cluster,
called Antennapedia complex and bithorax complex, located on the same chromosome arm …
called Antennapedia complex and bithorax complex, located on the same chromosome arm …
[HTML][HTML] Plug-and-play metabolic transducers expand the chemical detection space of cell-free biosensors
Cell-free transcription–translation systems have great potential for biosensing, yet the range
of detectable chemicals is limited. Here we provide a workflow to expand the range of …
of detectable chemicals is limited. Here we provide a workflow to expand the range of …
Rewritable digital data storage in live cells via engineered control of recombination directionality
J Bonnet, P Subsoontorn… - Proceedings of the …, 2012 - National Acad Sciences
The use of synthetic biological systems in research, healthcare, and manufacturing often
requires autonomous history-dependent behavior and therefore some form of engineered …
requires autonomous history-dependent behavior and therefore some form of engineered …
Detection of pathological biomarkers in human clinical samples via amplifying genetic switches and logic gates
Whole-cell biosensors have several advantages for the detection of biological substances
and have proven to be useful analytical tools. However, several hurdles have limited whole-…
and have proven to be useful analytical tools. However, several hurdles have limited whole-…
A part toolbox to tune genetic expression in Bacillus subtilis
…, C Clerté, N Declerck, M Jules, J Bonnet - Nucleic acids …, 2016 - academic.oup.com
Libraries of well-characterised components regulating gene expression levels are essential
to many synthetic biology applications. While widely available for the Gram-negative model …
to many synthetic biology applications. While widely available for the Gram-negative model …
Microbially derived biosensors for diagnosis, monitoring and epidemiology
…, PL Voyvodic, A Zúñiga, J Bonnet - Microbial …, 2017 - Wiley Online Library
Living cells have evolved to detect and process various signals and can self‐replicate,
presenting an attractive platform for engineering scalable and affordable biosensing devices. …
presenting an attractive platform for engineering scalable and affordable biosensing devices. …
[HTML][HTML] Metabolic perceptrons for neural computing in biological systems
Synthetic biological circuits are promising tools for developing sophisticated systems for
medical, industrial, and environmental applications. So far, circuit implementations commonly …
medical, industrial, and environmental applications. So far, circuit implementations commonly …
A modular receptor platform to expand the sensing repertoire of bacteria
…, P Minard, M Cohen-Gonsaud, J Bonnet - ACS synthetic …, 2018 - ACS Publications
Engineered bacteria promise to revolutionize diagnostics and therapeutics, yet many applications
are precluded by the limited number of detectable signals. Here we present a general …
are precluded by the limited number of detectable signals. Here we present a general …
Cell-free biosensors for biomedical applications
PL Voyvodic, J Bonnet - Current opinion in biomedical engineering, 2020 - Elsevier
Recent years have witnessed a rapid increase of the use of cell-free systems for biosensor
engineering. Building on the past decade of synthetic biology research mostly performed in …
engineering. Building on the past decade of synthetic biology research mostly performed in …