Modern molecular genetic datasets, primarily collected to study the biology of human health
and disease, can be used to directly measure the action of natural selection and reveal …

We gathered genomic data from grapes (Vitis vinifera ssp. vinifera), a clonally propagated
perennial crop, to address three ongoing mysteries about plant domestication. The first is the …

The genetic component of complex disease risk in humans remains largely unexplained. A
corollary is that the allelic spectrum of genetic variants contributing to complex disease risk is …

While evidence exists supporting the potential for aerosol transmission of SARS-CoV-2, the
infectious dose by inhalation remains unknown. In the present study, the probability of …

Background Radiation therapy is integral to effective thoracic cancer treatments, but its
application is limited by sensitivity of critical organs such as the heart. The impacts of acute …

Background The United Nations recently made a call to address the challenges of an estimated
300 million persons worldwide living with a rare disease through the collection, analysis, …

Gottingen minipigs mirror the physiological radiation response observed in humans and
hence make an ideal candidate model for studying radiation biodosimetry for both limited-sized …

Background Glioblastoma (GBM) is the most aggressive and common malignant primary
brain tumor; however, treatment remains a significant challenge. This study aims to identify …

Objective Identifying sets of rare diseases with shared aspects of etiology and pathophysiology
may enable drug repurposing. Toward that aim, we utilized an integrative knowledge …

Here, we provide revised gene models for D. ananassae, D. yakuba, and D. simulans, which
include untranslated regions and empirically verified intron-exon boundaries, as well as …