User profiles for James B. McKinlay

James McKinlay

Professor, Dept of Biology, Indiana University
Verified email at indiana.edu
Cited by 3249

Prospects for a bio-based succinate industry

JB McKinlay, C Vieille, JG Zeikus - Applied microbiology and …, 2007 - Springer
Bio-based succinate is receiving increasing attention as a potential intermediary feedstock
for replacing a large petrochemical-based bulk chemical market. The prospective economical …

Extracellular metabolism sets the table for microbial cross-feeding

RK Fritts, AL McCully, JB McKinlay - Microbiology and Molecular …, 2021 - Am Soc Microbiol
The transfer of nutrients between cells, or cross-feeding, is a ubiquitous feature of microbial
communities with emergent properties that influence our health and orchestrate global …

Microbial mutualism dynamics governed by dose-dependent toxicity of cross-fed nutrients

…, AL McCully, JT Lennon, JB McKinlay - The ISME …, 2017 - academic.oup.com
Microbial interactions, including mutualistic nutrient exchange (cross-feeding), underpin the
flow of energy and materials in all ecosystems. Metabolic exchanges are difficult to assess …

Carbon dioxide fixation as a central redox cofactor recycling mechanism in bacteria

JB McKinlay, CS Harwood - Proceedings of the National …, 2010 - National Acad Sciences
The Calvin-Benson-Bassham cycle (Calvin cycle) catalyzes virtually all primary productivity
on Earth and is the major sink for atmospheric CO 2 . A less appreciated function of CO 2 …

Determining Actinobacillus succinogenes metabolic pathways and fluxes by NMR and GC-MS analyses of 13C-labeled metabolic product isotopomers

JB McKinlay, Y Shachar-Hill, JG Zeikus, C Vieille - Metabolic engineering, 2007 - Elsevier
Actinobacillus succinogenes is a promising candidate for industrial succinate production.
However, in addition to producing succinate, it also produces formate and acetate. To …

[HTML][HTML] A genomic perspective on the potential of Actinobacillus succinogenes for industrial succinate production

JB McKinlay, M Laivenieks, BD Schindler, AA McKinlay… - BMC genomics, 2010 - Springer
Background Succinate is produced petrochemically from maleic anhydride to satisfy a small
specialty chemical market. If succinate could be produced fermentatively at a price …

Calvin cycle mutants of photoheterotrophic purple nonsulfur bacteria fail to grow due to an electron imbalance rather than toxic metabolite accumulation

GC Gordon, JB McKinlay - Journal of bacteriology, 2014 - Am Soc Microbiol
Purple nonsulfur bacteria grow photoheterotrophically by using light for energy and organic
compounds for carbon and electrons. Disrupting the activity of the CO 2 -fixing Calvin cycle …

Photobiological production of hydrogen gas as a biofuel

JB McKinlay, CS Harwood - Current opinion in biotechnology, 2010 - Elsevier
Solar energy can be converted into chemical energy in the form of hydrogen gas using oxygenic
and anoxygenic photosynthetic microbes. Laboratory-scale measurements suggest that …

Insights into Actinobacillus succinogenes Fermentative Metabolism in a Chemically Defined Growth Medium

JB McKinlay, JG Zeikus, C Vieille - Applied and environmental …, 2005 - Am Soc Microbiol
Chemically defined media allow for a variety of metabolic studies that are not possible with
undefined media. A defined medium, AM3, was created to expand the experimental …

Are bacteria leaky? Mechanisms of metabolite externalization in bacterial cross-feeding

JB McKinlay - Annual Review of Microbiology, 2023 - annualreviews.org
The metabolism of a bacterial cell stretches beyond its boundaries, often connecting with
the metabolism of other cells to form extended metabolic networks that stretch across …