User profiles for James B. McKinlay
James McKinlayProfessor, Dept of Biology, Indiana University Verified email at indiana.edu Cited by 3249 |
Prospects for a bio-based succinate industry
JB McKinlay, C Vieille, JG Zeikus - Applied microbiology and …, 2007 - Springer
Bio-based succinate is receiving increasing attention as a potential intermediary feedstock
for replacing a large petrochemical-based bulk chemical market. The prospective economical …
for replacing a large petrochemical-based bulk chemical market. The prospective economical …
Extracellular metabolism sets the table for microbial cross-feeding
The transfer of nutrients between cells, or cross-feeding, is a ubiquitous feature of microbial
communities with emergent properties that influence our health and orchestrate global …
communities with emergent properties that influence our health and orchestrate global …
Microbial mutualism dynamics governed by dose-dependent toxicity of cross-fed nutrients
Microbial interactions, including mutualistic nutrient exchange (cross-feeding), underpin the
flow of energy and materials in all ecosystems. Metabolic exchanges are difficult to assess …
flow of energy and materials in all ecosystems. Metabolic exchanges are difficult to assess …
Carbon dioxide fixation as a central redox cofactor recycling mechanism in bacteria
JB McKinlay, CS Harwood - Proceedings of the National …, 2010 - National Acad Sciences
The Calvin-Benson-Bassham cycle (Calvin cycle) catalyzes virtually all primary productivity
on Earth and is the major sink for atmospheric CO 2 . A less appreciated function of CO 2 …
on Earth and is the major sink for atmospheric CO 2 . A less appreciated function of CO 2 …
Determining Actinobacillus succinogenes metabolic pathways and fluxes by NMR and GC-MS analyses of 13C-labeled metabolic product isotopomers
Actinobacillus succinogenes is a promising candidate for industrial succinate production.
However, in addition to producing succinate, it also produces formate and acetate. To …
However, in addition to producing succinate, it also produces formate and acetate. To …
[HTML][HTML] A genomic perspective on the potential of Actinobacillus succinogenes for industrial succinate production
JB McKinlay, M Laivenieks, BD Schindler, AA McKinlay… - BMC genomics, 2010 - Springer
Background Succinate is produced petrochemically from maleic anhydride to satisfy a small
specialty chemical market. If succinate could be produced fermentatively at a price …
specialty chemical market. If succinate could be produced fermentatively at a price …
Calvin cycle mutants of photoheterotrophic purple nonsulfur bacteria fail to grow due to an electron imbalance rather than toxic metabolite accumulation
GC Gordon, JB McKinlay - Journal of bacteriology, 2014 - Am Soc Microbiol
Purple nonsulfur bacteria grow photoheterotrophically by using light for energy and organic
compounds for carbon and electrons. Disrupting the activity of the CO 2 -fixing Calvin cycle …
compounds for carbon and electrons. Disrupting the activity of the CO 2 -fixing Calvin cycle …
Photobiological production of hydrogen gas as a biofuel
JB McKinlay, CS Harwood - Current opinion in biotechnology, 2010 - Elsevier
Solar energy can be converted into chemical energy in the form of hydrogen gas using oxygenic
and anoxygenic photosynthetic microbes. Laboratory-scale measurements suggest that …
and anoxygenic photosynthetic microbes. Laboratory-scale measurements suggest that …
Insights into Actinobacillus succinogenes Fermentative Metabolism in a Chemically Defined Growth Medium
JB McKinlay, JG Zeikus, C Vieille - Applied and environmental …, 2005 - Am Soc Microbiol
Chemically defined media allow for a variety of metabolic studies that are not possible with
undefined media. A defined medium, AM3, was created to expand the experimental …
undefined media. A defined medium, AM3, was created to expand the experimental …
Are bacteria leaky? Mechanisms of metabolite externalization in bacterial cross-feeding
JB McKinlay - Annual Review of Microbiology, 2023 - annualreviews.org
The metabolism of a bacterial cell stretches beyond its boundaries, often connecting with
the metabolism of other cells to form extended metabolic networks that stretch across …
the metabolism of other cells to form extended metabolic networks that stretch across …