Pancreatic ductal adenocarcinoma (PDAC) remains a lethal disease with a 5-year survival
rate of 4%. A key hallmark of PDAC is extensive stromal involvement, which makes capturing …

We performed integrated genomic, transcriptomic, and proteomic profiling of 150 pancreatic
ductal adenocarcinoma (PDAC) specimens, including samples with characteristic low …

… A and B, Kaplan–Meier plots of OS in pooled datasets (A) belonging to the survival group
minus datasets belonging to the training group and Yeh Seq FNA samples (B). P value and …

Pancreatic ductal adenocarcinoma (PDAC) is notorious for a dense fibrotic stroma that is
interlaced with a collagen-based extracellular matrix (ECM) that plays an important role in …

We sought to define whether there are intrinsic molecular subtypes of high-grade bladder
cancer. Consensus clustering performed on gene expression data from a meta-dataset of high-…

The human gut microbiota is increasingly recognized as a player in colorectal cancer (CRC).
While particular imbalances in the gut microbiota have been linked to colorectal adenomas …

We describe a comprehensive genomic characterization of adrenocortical carcinoma (ACC).
Using this dataset, we expand the catalogue of known ACC driver genes to include …

Two decades after the discovery of the first animal microRNA (miRNA), the number of miRNAs
in animal genomes remains a vexing question. Here, we report findings from analyzing …

… JJ Yeh and RA Moffitt have a pending patent #15/518,900 with United States Patent and
Trademark Office on methods and compositions for prognostic and/or diagnostic subtyping of …

Despite major advancements in cancer treatments, there are still many limitations to therapy
including off-target effects, drug resistance, and control of cancer-related symptoms. There …