GENCODE: the reference human genome annotation for The ENCODE Project
J Harrow, A Frankish, JM Gonzalez, E Tapanari… - Genome …, 2012 - genome.cshlp.org
The GENCODE Consortium aims to identify all gene features in the human genome using a
combination of computational analysis, manual annotation, and experimental validation. …
combination of computational analysis, manual annotation, and experimental validation. …
The GENCODE v7 catalog of human long noncoding RNAs: analysis of their gene structure, evolution, and expression
…, TJ Hubbard, C Notredame, J Harrow… - Genome …, 2012 - genome.cshlp.org
The human genome contains many thousands of long noncoding RNAs (lncRNAs). While
several studies have demonstrated compelling biological and disease roles for individual …
several studies have demonstrated compelling biological and disease roles for individual …
[HTML][HTML] Landscape of transcription in human cells
…, J Wrobel, Y Yu, X Ruan, Y Hayashizaki, J Harrow… - Nature, 2012 - nature.com
Eukaryotic cells make many types of primary and processed RNAs that are found either in
specific subcellular compartments or throughout the cells. A complete catalogue of these …
specific subcellular compartments or throughout the cells. A complete catalogue of these …
A conditional knockout resource for the genome-wide study of mouse gene function
…, W Bushell, V Iyer, AO Mujica, M Thomas, J Harrow… - Nature, 2011 - nature.com
Gene targeting in embryonic stem cells has become the principal technology for manipulation
of the mouse genome, offering unrivalled accuracy in allele design and access to …
of the mouse genome, offering unrivalled accuracy in allele design and access to …
[HTML][HTML] Analyses of pig genomes provide insight into porcine demography and evolution
For 10,000 years pigs and humans have shared a close and complex relationship. From
domestication to modern breeding practices, humans have shaped the genomes of domestic …
domestication to modern breeding practices, humans have shaped the genomes of domestic …
Ensembl 2015
Ensembl ( http://www.ensembl.org ) is a genomic interpretation system providing the most up-to-date
annotations, querying tools and access methods for chordates and key model …
annotations, querying tools and access methods for chordates and key model …
Ensembl 2016
…, SP Wilder, A Zadissa, E Birney, J Harrow… - Nucleic acids …, 2016 - academic.oup.com
The Ensembl project ( http://www.ensembl.org ) is a system for genome annotation, analysis,
storage and dissemination designed to facilitate the access of genomic annotation from …
storage and dissemination designed to facilitate the access of genomic annotation from …
Ensembl 2014
…, E Birney, F Cunningham, J Harrow… - Nucleic acids …, 2014 - academic.oup.com
Ensembl ( http://www.ensembl.org ) creates tools and data resources to facilitate genomic
analysis in chordate species with an emphasis on human, major vertebrate model organisms …
analysis in chordate species with an emphasis on human, major vertebrate model organisms …
A systematic survey of loss-of-function variants in human protein-coding genes
Genome-sequencing studies indicate that all humans carry many genetic variants predicted
to cause loss of function (LoF) of protein-coding genes, suggesting unexpected redundancy …
to cause loss of function (LoF) of protein-coding genes, suggesting unexpected redundancy …
Ensembl 2012
…, XM Fernández-Suarez, J Harrow… - Nucleic acids …, 2012 - academic.oup.com
The Ensembl project ( http://www.ensembl.org ) provides genome resources for chordate
genomes with a particular focus on human genome data as well as data for key model …
genomes with a particular focus on human genome data as well as data for key model …