GENCODE: the reference human genome annotation for The ENCODE Project

J Harrow, A Frankish, JM Gonzalez, E Tapanari… - Genome …, 2012 - genome.cshlp.org
The GENCODE Consortium aims to identify all gene features in the human genome using a
combination of computational analysis, manual annotation, and experimental validation. …

The GENCODE v7 catalog of human long noncoding RNAs: analysis of their gene structure, evolution, and expression

…, TJ Hubbard, C Notredame, J Harrow… - Genome …, 2012 - genome.cshlp.org
The human genome contains many thousands of long noncoding RNAs (lncRNAs). While
several studies have demonstrated compelling biological and disease roles for individual …

[HTML][HTML] Landscape of transcription in human cells

…, J Wrobel, Y Yu, X Ruan, Y Hayashizaki, J Harrow… - Nature, 2012 - nature.com
Eukaryotic cells make many types of primary and processed RNAs that are found either in
specific subcellular compartments or throughout the cells. A complete catalogue of these …

A conditional knockout resource for the genome-wide study of mouse gene function

…, W Bushell, V Iyer, AO Mujica, M Thomas, J Harrow… - Nature, 2011 - nature.com
Gene targeting in embryonic stem cells has become the principal technology for manipulation
of the mouse genome, offering unrivalled accuracy in allele design and access to …

[HTML][HTML] Analyses of pig genomes provide insight into porcine demography and evolution

…, E Giuffra, J Gorodkin, DK Griffin, JL Harrow… - Nature, 2012 - nature.com
For 10,000 years pigs and humans have shared a close and complex relationship. From
domestication to modern breeding practices, humans have shaped the genomes of domestic …

Ensembl 2015

…, A Zadissa, BL Aken, E Birney, J Harrow… - Nucleic acids …, 2015 - academic.oup.com
Ensembl ( http://www.ensembl.org ) is a genomic interpretation system providing the most up-to-date
annotations, querying tools and access methods for chordates and key model …

Ensembl 2016

…, SP Wilder, A Zadissa, E Birney, J Harrow… - Nucleic acids …, 2016 - academic.oup.com
The Ensembl project ( http://www.ensembl.org ) is a system for genome annotation, analysis,
storage and dissemination designed to facilitate the access of genomic annotation from …

Ensembl 2014

…, E Birney, F Cunningham, J Harrow… - Nucleic acids …, 2014 - academic.oup.com
Ensembl ( http://www.ensembl.org ) creates tools and data resources to facilitate genomic
analysis in chordate species with an emphasis on human, major vertebrate model organisms …

A systematic survey of loss-of-function variants in human protein-coding genes

…, ET Dermitzakis, JK Pritchard, JC Barrett, J Harrow… - Science, 2012 - science.org
Genome-sequencing studies indicate that all humans carry many genetic variants predicted
to cause loss of function (LoF) of protein-coding genes, suggesting unexpected redundancy …

Ensembl 2012

…, XM Fernández-Suarez, J Harrow… - Nucleic acids …, 2012 - academic.oup.com
The Ensembl project ( http://www.ensembl.org ) provides genome resources for chordate
genomes with a particular focus on human genome data as well as data for key model …