Universal protection against influenza infection by a multidomain antibody to influenza hemagglutinin
Broadly neutralizing antibodies against highly variable pathogens have stimulated the
design of vaccines and therapeutics. We report the use of diverse camelid single-domain …
design of vaccines and therapeutics. We report the use of diverse camelid single-domain …
Structure-based engineering of a monoclonal antibody for improved solubility
SJ Wu, J Luo, KT O'Neil, J Kang, ER Lacy… - … , Design & Selection, 2010 - academic.oup.com
Protein aggregation is of great concern to pharmaceutical formulations and has been implicated
in several diseases. We engineered an anti-IL-13 monoclonal antibody CNTO607 for …
in several diseases. We engineered an anti-IL-13 monoclonal antibody CNTO607 for …
Structural basis for the dual recognition of IL-12 and IL-23 by ustekinumab
J Luo, SJ Wu, ER Lacy, Y Orlovsky, A Baker… - Journal of molecular …, 2010 - Elsevier
Interleukin (IL)-12 and IL-23 are heterodimeric proinflammatory cytokines that share a common
p40 subunit, paired with p35 and p19 subunits, respectively. They represent an attractive …
p40 subunit, paired with p35 and p19 subunits, respectively. They represent an attractive …
On the weight distributions of two classes of cyclic codes
J Luo, K Feng - IEEE Transactions on Information Theory, 2008 - ieeexplore.ieee.org
Let q=p m where p is an odd prime, mges2, and 1lesklesm-1. Let Tr be the trace mapping
from F q to F p and zeta p =e 2pii/p be a primitive pth root of unity. In this paper, we determine …
from F q to F p and zeta p =e 2pii/p be a primitive pth root of unity. In this paper, we determine …
Application of classical Hermitian self-orthogonal MDS codes to quantum MDS codes
In this paper, we first construct several classes of classical Hermitian self-orthogonal maximum
distance separable (MDS) codes. Through these classical codes, we are able to obtain …
distance separable (MDS) codes. Through these classical codes, we are able to obtain …
Weight distribution of some reducible cyclic codes
K Feng, J Luo - Finite Fields and Their Applications, 2008 - Elsevier
Let q=p m where p is an odd prime, m⩾3, k⩾1 and gcd(k,m)=1. Let Tr be the trace mapping
from F q to F p and ζ p =e 2πip . In this paper we determine the value distribution of following …
from F q to F p and ζ p =e 2πip . In this paper we determine the value distribution of following …
Cyclic codes and sequences from generalized Coulter–Matthews function
J Luo, K Feng - IEEE transactions on information theory, 2008 - ieeexplore.ieee.org
In this paper, we will study the exponential sum SigmaxisinF q x(alphax(p k +1)/2+betax) that
is related to the generalized Coulter-Matthews function x(pk+1)/2 with k/gcd. As applications…
is related to the generalized Coulter-Matthews function x(pk+1)/2 with k/gcd. As applications…
A family of five-weight cyclic codes and their weight enumerators
Cyclic codes are a subclass of linear codes and have applications in consumer electronics,
data storage systems, and communication systems as they have efficient encoding and …
data storage systems, and communication systems as they have efficient encoding and …
Second antibody modeling assessment (AMA‐II)
JC Almagro, A Teplyakov, J Luo… - Proteins: Structure …, 2014 - Wiley Online Library
To assess the state of the art in antibody 3D modeling, 11 unpublished high‐resolution x‐ray
Fab crystal structures from diverse species and covering a wide range of antigen‐binding …
Fab crystal structures from diverse species and covering a wide range of antigen‐binding …
Epitope mapping and structural basis for the recognition of phosphorylated tau by the anti‐tau antibody AT8
…, M Vandermeeren, M Mercken, J Luo… - Proteins: Structure …, 2016 - Wiley Online Library
Microtubule‐associated protein tau becomes abnormally phosphorylated in Alzheimer's
disease and other tauopathies and forms aggregates of paired helical filaments (PHF‐tau). AT8 …
disease and other tauopathies and forms aggregates of paired helical filaments (PHF‐tau). AT8 …