User profiles for Jordan Burke

Jordan Burke

- Verified email at ucsf.edu - Cited by 706

Jordan L. Burke

- Verified email at alumni.ubc.ca - Cited by 121

[PDF][PDF] Evolutionary persistence of DNA methylation for millions of years after ancient loss of a de novo methyltransferase

…, H Pimentel, A Nasif, CI Stoddard, JE Burke… - Cell, 2020 - cell.com
Cytosine methylation of DNA is a widespread modification of DNA that plays numerous
critical roles. In the yeast Cryptococcus neoformans, CG methylation occurs in transposon-rich …

Structure of the yeast U2/U6 snRNA complex

JE Burke, DG Sashital, X Zuo, YX Wang, SE Butcher - Rna, 2012 - rnajournal.cshlp.org
The U2/U6 snRNA complex is a conserved and essential component of the active spliceosome
that interacts with the pre-mRNA substrate and essential protein splicing factors to …

Structural mechanisms of DNA binding and unwinding in bacterial RecQ helicases

KA Manthei, MC Hill, JE Burke… - Proceedings of the …, 2015 - National Acad Sciences
RecQ helicases unwind remarkably diverse DNA structures as key components of many
cellular processes. How RecQ enzymes accommodate different substrates in a unified …

[PDF][PDF] Spliceosome profiling visualizes operations of a dynamic RNP at nucleotide resolution

JE Burke, AD Longhurst, D Merkurjev, J Sales-Lee… - Cell, 2018 - cell.com
Tools to understand how the spliceosome functions in vivo have lagged behind advances in
the structural biology of the spliceosome. Here, methods are described to globally profile …

Structural analysis of multi-helical RNAs by NMR–SAXS/WAXS: application to the U4/U6 di-snRNA

…, ML Rodgers, LA Michael, JE Burke… - Journal of Molecular …, 2016 - Elsevier
NMR and SAXS (small-angle X-ray scattering)/WAXS (wide-angle X-ray scattering) are
highly complementary approaches for the analysis of RNA structure in solution. Here we …

Polymerase pausing induced by sequence-specific RNA-binding protein drives heterochromatin assembly

JY Parsa, S Boudoukha, J Burke, C Homer… - Genes & …, 2018 - genesdev.cshlp.org
In Schizosaccharomyces pombe, transcripts derived from the pericentromeric dg and dh
repeats promote heterochromatin formation via RNAi as well as an RNAi-independent …

Cooperation and coordination in plant disease management

J Sherman, JM Burke, DH Gent - Phytopathology, 2019 - Am Phytopath Society
Scaling of management efforts beyond the boundaries of individual farms may require that
individuals act collectively. Such approaches have been suggested several times in plant …

Consequences of distributional asymmetry in a warming environment: invasion of novel forests by the mountain pine beetle

JL Burke, J Bohlmann, AL Carroll - Ecosphere, 2017 - Wiley Online Library
The range of many Holarctic forest insects does not comprise the entire range of their hosts,
as they are often limited to more southern latitudes by the adverse effects of cold …

The influence of variation in host tree monoterpene composition on secondary attraction by an invasive bark beetle: implications for range expansion and potential …

JL Burke, AL Carroll - Forest Ecology and Management, 2016 - Elsevier
The range of mountain pine beetle (Dendroctonus ponderosae) has expanded in recent
years to include many evolutionarily naïve forests in western Canada. These forests include …

[PDF][PDF] Pathogenic TFG mutations underlying hereditary spastic paraplegia impair secretory protein trafficking and axon fasciculation

…, EB Frankel, N Bhattacharya, MG Hanna, JE Burke… - Cell reports, 2018 - cell.com
Length-dependent axonopathy of the corticospinal tract causes lower limb spasticity and is
characteristic of several neurological disorders, including hereditary spastic paraplegia (HSP…