Dominantly inherited Alzheimer’s disease (DIAD) causes predictable biological changes
decades before the onset of clinical symptoms, enabling testing of interventions in the …

Background With no effective treatments for cognitive decline or dementia, improving the
evidence base for modifiable risk factors is a research priority. This study investigated …

Background The World Health Organization (WHO) has reframed health and healthcare for
older people around achieving the goal of healthy ageing. The recent WHO Integrated Care …

Alzheimer disease (AD) prevention trials hold the promise to delay or prevent cognitive decline
and dementia onset by intervening before significant neuronal damage occurs. In recent …

The recent global severe acute respiratory syndrome coronavirus 2 pandemic will leave its
shadow over mental health in our society, especially among the most vulnerable such as …

Background Age and gender specific prevalence rates for parkinsonism and Parkinson's
disease (PD) are important to guide research, clinical practice, and public health planning; …

INTRODUCTION Population aging translates into more people with chronic non-communicable
diseases, disability, frailty and dependency. The study of frailty-a clinical syndrome …

Objective To determine the characteristics of participants with amyloid‐related imaging
abnormalities (ARIA) in a trial of gantenerumab or solanezumab in dominantly inherited …

Background Parkinson's disease (PD) is a rapidly growing neurodegenerative disorder, but
up‐to‐date epidemiological data are lacking in Latin America. We sought to estimate the …

Aging and Alzheimer is a prospective, longitudinal cohort study involving 2944 adults aged
≥65 years from selected areas in Cuba’s Havana and Matanzas Provinces. This door-to-…