User profiles for Karim Gharbi

Karim Gharbi

Earlham Institute
Verified email at earlham.ac.uk
Cited by 9445

Deciphering mollusc shell production: the roles of genetic mechanisms through to ecology, aquaculture and biomimetics

…, G Chapelle, M De Noia, S Dupont, K Gharbi… - Biological …, 2020 - Wiley Online Library
Most molluscs possess shells, constructed from a vast array of microstructures and architectures.
The fully formed shell is composed of calcite or aragonite. These CaCO 3 crystals form …

How many biological replicates are needed in an RNA-seq experiment and which differential expression tool should you use?

…, C Cole, A Sherstnev, V Singh, N Wrobel, K Gharbi… - Rna, 2016 - rnajournal.cshlp.org
RNA-seq is now the technology of choice for genome-wide differential gene expression
experiments, but it is not clear how many biological replicates are needed to ensure valid …

A Microsatellite Linkage Map of Rainbow Trout (Oncorhynchus mykiss) Characterized by Large Sex-Specific Differences in Recombination Rates

T Sakamoto, RG Danzmann, K Gharbi, P Howard… - Genetics, 2000 - academic.oup.com
We constructed a genetic linkage map for a tetraploid derivative species, the rainbow trout (Oncorhynchus
mykiss), using 191 microsatellite, 3 RAPD, 7 ESMP, and 7 allozyme markers …

Special features of RAD Sequencing data: implications for genotyping

…, P Fuentes‐Utrilla, C Eland, K Gharbi… - Molecular …, 2013 - Wiley Online Library
Restriction site‐associated DNA Sequencing ( RAD ‐Seq) is an economical and efficient
method for SNP discovery and genotyping. As with other sequencing‐by‐synthesis methods, …

The effect of RAD allele dropout on the estimation of genetic variation within and between populations

M Gautier, K Gharbi, T Cezard, J Foucaud… - Molecular …, 2013 - Wiley Online Library
Inexpensive short‐read sequencing technologies applied to reduced representation genomes
is revolutionizing genetic research, especially population genetics analysis, by allowing …

[HTML][HTML] Development and validation of a high density SNP genotyping array for Atlantic salmon (Salmo salar)

…, DJ Penman, A Davassi, F Brew, AE Tinch, K Gharbi… - BMC genomics, 2014 - Springer
Background Dense single nucleotide polymorphism (SNP) genotyping arrays provide
extensive information on polymorphic variation across the genome of species of interest. Such …

Comparative genome analysis of the primary sex-determining locus in salmonid fishes

RA Woram, K Gharbi, T Sakamoto, B Hoyheim… - Genome …, 2003 - genome.cshlp.org
We compared the Y-chromosome linkage maps for four salmonid species (Arctic charr,
Salvelinus alpinus; Atlantic salmon, Salmo salar; brown trout, Salmo trutta; and rainbow trout,…

Estimation of population allele frequencies from next‐generation sequencing data: pool‐versus individual‐based genotyping

M Gautier, J Foucaud, K Gharbi, T Cézard… - Molecular …, 2013 - Wiley Online Library
Molecular markers produced by next‐generation sequencing ( NGS ) technologies are
revolutionizing genetic research. However, the costs of analysing large numbers of individual …

[HTML][HTML] Genome wide association and genomic prediction for growth traits in juvenile farmed Atlantic salmon using a high density SNP array

HY Tsai, A Hamilton, AE Tinch, DR Guy, K Gharbi… - BMC genomics, 2015 - Springer
Background The genetic architecture of complex traits in farmed animal populations is of
interest from a scientific and practical perspective. The use of genetic markers to predict the …

[HTML][HTML] Mapping and Validation of the Major Sex-Determining Region in Nile Tilapia (Oreochromis niloticus L.) Using RAD Sequencing

…, M Bekaert, MGQ Khan, JB Taggart, K Gharbi… - PloS one, 2013 - journals.plos.org
Sex in Oreochromis niloticus (Nile tilapia) is principally determined by an XX/XY locus but
other genetic and environmental factors also influence sex ratio. Restriction Associated DNA (…