Here we conducted a large-scale genetic association analysis of educational attainment in
a sample of approximately 1.1 million individuals and identify 1,271 independent genome-…

To identify common variants influencing body mass index (BMI), we analyzed genome-wide
association data from 16,876 individuals of European descent. After previously reported …

In a systematic review, we identified 21 separate studies with data on the association between
rapid infancy weight gain, up to age 2 y, and subsequent obesity risk. Uniformly all studies …

Waist-hip ratio (WHR) is a measure of body fat distribution and a predictor of metabolic
consequences independent of overall adiposity. WHR is heritable, but few genetic variants …

Triglycerides are transported in plasma by specific triglyceride-rich lipoproteins; in
epidemiological studies, increased triglyceride levels correlate with higher risk for coronary artery …

Recent genome-wide association studies have described many loci implicated in type 2
diabetes (T2D) pathophysiology and β-cell dysfunction but have contributed little to the …

Background— DNA methylation leaves a long-term signature of smoking exposure and is one
potential mechanism by which tobacco exposure predisposes to adverse health outcomes…

Evidence for a major role of genetic factors in the determination of body mass index (BMI)
comes from studies of related individuals. Despite consistent evidence for a heritable …

Context: The relationship between age at menarche and cardiovascular disease remains
unclear. Two recent studies found an inverse association between age at menarche and all-…

Strong associations between low birth weight and insulin resistance have been described.
However, most of these studies have been retrospective. We aimed to determine whether …