Background Treatment of hypertension with diuretics, beta-blockers, or both leads to improved
outcomes. It has been postulated that agents that inhibit the renin–angiotensin system …

In light of the worldwide epidemic of obesity, and in recognition of hypertension as a major
factor in the cardiovascular morbidity and mortality associated with obesity, The Obesity …

Background Aspirin is a well-established therapy for the secondary prevention of cardiovascular
events. However, its role in the primary prevention of cardiovascular disease is unclear, …

Background In the primary analysis of the Aspirin in Reducing Events in the Elderly (ASPREE)
trial, now published in the Journal, we report that the daily use of aspirin did not provide a …

Background: Regular consumption of n−3 fatty acids of marine origin can improve serum
lipids and reduce cardiovascular risk. Objective: This study aimed to determine whether …

59 healthy, omnivorous subjects aged 25-63 years were randomly allocated to a control group,
which ate an omnivorous diet for 14 weeks, or to one of two experimental groups, whose …

Animal studies suggest that the 2 major ω3 fatty acids found in fish, eicosapentaenoic acid (EPA)
and docosahexaenoic acid (DHA), may have differential effects on blood pressure (BP) …

BACKGROUND: There is growing interest in the potential role of anti-inflammatory n-3
polyunsaturated fatty acids (n-3 PUFAs) in the prevention of allergic disease. OBJECTIVE: We …

Dietary omega-3 (n-3) fatty acids have a variety of anti-inflammatory and immune-modulating
effects that may be of relevance to atherosclerosis and its clinical manifestations of …

n-3 Fatty acids reduce the risk of cardiovascular disease via a number of possible
mechanisms. Despite this, there has been concern that these fatty acids may increase lipid …