User profiles for Lin Li

LI LIN

Peking university
Verified email at pku.edu.cn
Cited by 6272

Clinical and biological features associated with epidermal growth factor receptor gene mutations in lung cancers

H Shigematsu, L Lin, T Takahashi… - Journal of the …, 2005 - academic.oup.com
Background: Mutations in the tyrosine kinase (TK) domain of the epidermal growth factor
receptor (EGFR) gene in lung cancers are associated with increased sensitivity of these …

[HTML][HTML] Genome-wide profiling of 5-formylcytosine reveals its roles in epigenetic priming

…, Q Dai, Y Fu, SQ Mao, L Lin, C Street, Y Li… - Cell, 2013 - cell.com
TET proteins oxidize 5-methylcytosine (5mC) to 5-hydroxymethylcytosine (5hmC), 5-formylcytosine
(5fC), and 5-carboxylcytosine (5caC). 5fC and 5caC are excised by mammalian DNA …

Synthesis challenges for graphene industry

L Lin, H Peng, Z Liu - Nature materials, 2019 - nature.com
The past few years have witnessed significant development in graphene research, yet a
number of challenges remain for its commercialization and industrialization. This Comment …

ID-Score: a new empirical scoring function based on a comprehensive set of descriptors related to protein–ligand interactions

GB Li, LL Yang, WJ Wang, LL Li… - Journal of chemical …, 2013 - ACS Publications
Scoring functions have been widely used to assess protein–ligand binding affinity in
structure-based drug discovery. However, currently commonly used scoring functions face some …

Simultaneous Fenton‐like Ion Delivery and Glutathione Depletion by MnO2‐Based Nanoagent to Enhance Chemodynamic Therapy

LS Lin, J Song, L Song, K Ke, Y Liu, Z Zhou… - Angewandte …, 2018 - Wiley Online Library
Chemodynamic therapy (CDT) utilizes iron‐initiated Fenton chemistry to destroy tumor cells
by converting endogenous H 2 O 2 into the highly toxic hydroxyl radical ( . OH). There is a …

[PDF][PDF] Brain-region-specific organoids using mini-bioreactors for modeling ZIKV exposure

…, F Jacob, C Zhong, K Yoon, W Jeang, L Lin, Y Li… - Cell, 2016 - cell.com
Cerebral organoids, three-dimensional cultures that model organogenesis, provide a new
platform to investigate human brain development. High cost, variability, and tissue …

Recent progress on two-dimensional materials

…, Y Huang, W Ji, D Li, LJ Li, Q Li, L Lin… - Wuli Huaxue Xuebao …, 2021 - hub.hku.hk
Research on two-dimensional (2D) materials has been explosively increasing in last seventeen
years in varying subjects including condensed matter physics, electronic engineering, …

[HTML][HTML] Cotranslational biogenesis of NF-κB p50 by the 26S proteasome

L Lin, GN DeMartino, WC Greene - Cell, 1998 - cell.com
The NFKB1 gene encodes two functionally distinct proteins termed p50 and p105. p50
corresponds to the N terminus of p105 and with p65 (RelA) forms the prototypical NF-κB …

An overview on assessing agreement with continuous measurements

HX Barnhart, MJ Haber, LI Lin - Journal of biopharmaceutical …, 2007 - Taylor & Francis
… MSD total and MSD intra reduce to the MSD total (Lin) and MSD intra (Lin), respectively and
the general MSD inter is the limit of Lin's MSD inter (Lin) as K → ∞. It would be of interest to …

[HTML][HTML] Artificial intelligence distinguishes COVID-19 from community acquired pneumonia on chest CT

L Li, L Qin, Z Xu, Y Yin, X Wang, B Kong, J Bai, Y Lu… - Radiology, 2020 - ncbi.nlm.nih.gov
Background Coronavirus disease has widely spread all over the world since the beginning
of 2020. It is desirable to develop automatic and accurate detection of COVID-19 using chest …