Stat91 (a 91 kd protein that acts as a slgnal transducer and activator of transcription) is
inactive in the cytoplasm of untreated cells but is activated by phosphorylation on tyrosine in …

Diabetes is associated with increased prevalence, severity, and progression of periodontal
disease. To test the hypothesis that activation of RAGE (Receptor for Advanced Glycation …

The movement of many transcription factors, kinases and replication factors between the
nucleus and cytoplasm is important in regulating their activity 1 . In some cases, …

Heterotrimeric guanosine triphosphate (GTP)–binding proteins (G proteins) determine tissue
and cell polarity in a variety of organisms. In yeast, cells orient polarized growth toward the …

Drug target identification is a crucial step in development, yet is also among the most
complex. To address this, we develop BANDIT, a Bayesian machine-learning approach that …

During Caenorhabditis elegans vulval development, an inductive signal from the anchor
cell stimulates three of the six vulval precursor cells (VPCs) to adopt vulval rather than …

Diabetes is a risk factor for periodontal disease in humans. In hyperglycemia, glycoxidation
of proteins and lipids results in the formation of advanced glycation endproducts, or AGEs. …

Objective: This paper describes the Precision Medicine Knowledge Base (PMKB; https://pmkb.weill.cornell.edu
), an interactive online application for collaborative editing, maintenance, …

The late phase of long‐term potentiation (LTP) requires activation of the mammalian target
of rapamycin (mTOR) pathway and synthesis of new proteins. mTOR regulates protein …

Background and Objective: A prototype ultrawide field angiographic system and
conventional technology were compared. Patients and Methods: Thirty subjects with diabetic …