[HTML][HTML] Crystal structure of TET2-DNA complex: insight into TET-mediated 5mC oxidation
TET proteins oxidize 5-methylcytosine (5mC) on DNA and play important roles in various
biological processes. Mutations of TET2 are frequently observed in myeloid malignance. Here, …
biological processes. Mutations of TET2 are frequently observed in myeloid malignance. Here, …
Structural insight into substrate preference for TET-mediated oxidation
DNA methylation is an important epigenetic modification 1 , 2 , 3 . Ten-eleven translocation (TET)
proteins are involved in DNA demethylation through iteratively oxidizing 5-…
proteins are involved in DNA demethylation through iteratively oxidizing 5-…
[PDF][PDF] N6-deoxyadenosine methylation in mammalian mitochondrial DNA
N 6 -Methyldeoxyadenosine (6mA) has recently been shown to exist and play regulatory
roles in eukaryotic genomic DNA (gDNA). However, the biological functions of 6mA in …
roles in eukaryotic genomic DNA (gDNA). However, the biological functions of 6mA in …
[HTML][HTML] Crystal structure of PHD domain of UHRF1 and insights into recognition of unmodified histone H3 arginine residue 2
H3K4 reduced binding affinity by approximately threefold, suggesting that H3K4 may not be
involved in or plays a minor role for the specific interaction with PHDUHRF1. In contrast, ITC …
involved in or plays a minor role for the specific interaction with PHDUHRF1. In contrast, ITC …
m6A-SAC-seq for quantitative whole transcriptome m6A profiling
N 6 -methyladenosine (m 6 A) is the most abundant mRNA modification in mammalian cells,
regulating many physiological processes. Here we describe a method for base-resolution, …
regulating many physiological processes. Here we describe a method for base-resolution, …
m6A RNA modifications are measured at single-base resolution across the mammalian transcriptome
Functional studies of the RNA N 6 -methyladenosine (m 6 A) modification have been limited
by an inability to map individual m 6 A-modified sites in whole transcriptomes. To enable …
by an inability to map individual m 6 A-modified sites in whole transcriptomes. To enable …
[PDF][PDF] Transcriptome-wide mapping of internal N7-methylguanosine methylome in mammalian mRNA
N 7 -methylguanosine (m 7 G) is a positively charged, essential modification at the 5′ cap
of eukaryotic mRNA, regulating mRNA export, translation, and splicing. m 7 G also occurs …
of eukaryotic mRNA, regulating mRNA export, translation, and splicing. m 7 G also occurs …
[PDF][PDF] PHD finger recognition of unmodified histone H3R2 links UHRF1 to regulation of euchromatic gene expression
Histone methylation occurs on both lysine and arginine residues, and its dynamic regulation
plays a critical role in chromatin biology. Here we identify the UHRF1 PHD finger (PHD …
plays a critical role in chromatin biology. Here we identify the UHRF1 PHD finger (PHD …
Carbon dots as fillers inducing healing/self‐healing and anticorrosion properties in polymers
Self‐healing is the way by which nature repairs damage and prolongs the life of bio entities.
A variety of practical applications require self‐healing materials in general and self‐healing …
A variety of practical applications require self‐healing materials in general and self‐healing …
Inert filler selection strategies in Li-ion gel polymer electrolytes
J Pan, P Zhao, H Yao, L Hu, HJ Fan - ACS Applied Materials & …, 2023 - ACS Publications
The main role of inert fillers in polymer electrolytes is to enhance ionic conductivity. However,
lithium ions in gel polymer electrolytes (GPEs) conduct in liquid solvent rather than along …
lithium ions in gel polymer electrolytes (GPEs) conduct in liquid solvent rather than along …