Phenotype prediction in an Escherichia coli strain panel

M Galardin, A Koumoutsi, L Herrera-Dominguez… - bioRxiv, 2017 - biorxiv.org
Understanding how genetic variation contributes to phenotypic differences is a fundamental
question in biology. Here, we set to predict fitness defects of an individual using mechanistic …

Experimental etch-and-rinse adhesive systems containing MMP-inhibitors: Physicochemical characterization and resin-dentin bonding stability

EM da Silva, CUF de Sá Rodrigues… - Journal of dentistry, 2015 - Elsevier
… modified with 5 μM of Galardin were not able to maintain resin–… Galardin and hybridized
with an etch-and-rinse adhesive system. Thus, it is speculated that the concentration of Galardin

Combining in silico tools and NMR data to validate protein− ligand structural models: application to matrix metalloproteinases

I Bertini, M Fragai, A Giachetti, C Luchinat… - Journal of medicinal …, 2005 - ACS Publications
Galardin (see Chart 1) is a broad spectrum peptidomimetic inhibitor of MMPs 16 with an IC
… Figure 7 Representative structures of the MMP-1−galardin adduct for the four lowest energy …

[HTML][HTML] Permeability analyses and three dimensional imaging of interferon gamma-induced barrier disintegration in intestinal organoids

M Bardenbacher, B Ruder, N Britzen-Laurent… - Stem cell …, 2019 - Elsevier
… (B) In organoids from IFN-γR2 ΔIEC mice neither treatment with IFN-γ nor galardin changed
the localization of c-2, c-7 and c-15. The scale bar represents 10 μm. (For interpretation of …

Multiple pathways mediate luteinizing hormone regulation of cGMP signaling in the mouse ovarian follicle

X Liu, F Xie, AM Zamah, B Cao… - Biology of …, 2014 - academic.oup.com
Luteinizing hormone (LH) regulation of the epidermal growth factor (EGF) network is critical
for oocyte maturation and the ovulatory process. Recent studies have indicated that C-type …

Exploring the subtleties of drug− receptor interactions: the case of matrix metalloproteinases

I Bertini, V Calderone, M Fragai… - Journal of the …, 2007 - ACS Publications
… Two other well-known strong MMP ligands, actinonin and galardin (Biomol Inc.), were also
… For instance, galardin and actinonin, two well-known strong inhibitors of MMPs, show much …

[PDF][PDF] Roles of Matrix Metalloproteinases in Periodontal Diseases and Dental Caries

E Allam, S Feitosa, J Palasuk… - … and Roles in …, 2015 - novapublishers.com
… The inhibitory effects of galardin on MMP-2 and MMP-9 activity were assayed by gelatin …
the galardin-treated group. Interfacial nanoleakage revealed reduced silver deposits in galardin-…

Pharmacomodulation of broad spectrum matrix metalloproteinase inhibitors towards regulation of gelatinases

E Bourguet, AJP Alix, G Moroy, J Sapi… - Enzyme Inhibition …, 2012 - books.google.com
… Inhibition of MMP and serine elastases by oleic acid and oleoyl-galardin® derivatives.
MMP (Kis values are expressed in μM), HLE and plasmin (IC50 values are expressed in μM). …

Diverse and productive source of biopolymer inspiration: Marine collagens

D Fassini, IC Wilkie, M Pozzolini, C Ferrario… - …, 2021 - ACS Publications
… (96) The effects of a synthetic MMP inhibitor, galardin, on the mechanical properties of sea
urchin ligaments in different mechanical states provided evidence that MMP-like molecules …

Nanotube-modified dentin adhesive—Physicochemical and dentin bonding characterizations

MC Bottino, G Batarseh, J Palasuk, MS Alkatheeri… - Dental Materials, 2013 - Elsevier
Objective The aim of this study was to investigate the effect of aluminosilicate clay nanotubes
(Halloysite, HNT) incorporated into the adhesive resin of a commercially available three-…