Chaperonin 60 is the prototypic molecular chaperone, an essential protein in eukaryotes
and prokaryotes, whose sequence conservation provides an excellent basis for phylogenetic …

NaCl-saturated brines such as saltern crystalliser ponds, inland salt lakes, deep-sea brines
and liquids-of-deliquescence on halite are commonly regarded as a paradigm for the limit of …

Many eukaryotic organisms have symbiotic associations with obligate intracellular bacteria.
The clonal transmission of endosymbionts between host generations should lead to the …

GroEL, a heat-shock protein that acts as a molecular chaperone 1 , is overproduced in
endosymbiotic but not in free-living bacteria 2 , 3 , 4 , presumably to assist in the folding of …

Antimicrobial peptides (AMPs) are essential components of innate immunity in a range of
species from Drosophila to humans and are generally thought to act by disrupting the …

These studies demonstrate that CSF-1 and IL-34 are conserved in birds, and uses
evolutionary comparisons to infer structure function relationships among vertebrate animals. …

Protein evolution depends on intramolecular coevolutionary networks whose complexity is
proportional to the underlying functional and structural interactions among sites. Here we …

Coevolution Analysis using Protein Sequences (CAPS) is a PERL based software that
identifies co-evolution between amino acid sites. Blosum-corrected amino acid distances are …

Previous studies of the evolutionary history of hepatitis B virus (HBV) have been compromised
by intergenotype recombination and complex patterns of nucleotide substitution, perhaps …

Background Candida glabrata is a pathogenic yeast of increasing medical concern. It has
been regarded as asexual since it was first described in 1917, yet phylogenetic analyses have …