The complete nucleotide sequence of two human T-cell leukaemia type III (HTLV-III) proviral
DNAs each have four long open reading frames, the first two corresponding to the gag and …

Insulin-like growth factors and their receptor (IGF-1R) have been implicated in cancer
pathophysiology. We demonstrate that IGF-1R is universally expressed in various hematologic (…

IGF-IR-mediated signaling promotes survival, anchorage-independent growth, and oncogenic
transformation, as well as tumor growth and metastasis formation in vivo. NVP-AEW541 is …

Schistosomes are blood-dwelling flukes that infect 200 million people worldwide and are
responsible for hundreds of thousands of deaths annually 1 . Using a signal sequence trap, we …

Objective In the majority of patients with rheumatoid arthritis (RA), antibodies specifically
recognize citrullinated autoantigens that are generated by peptidylarginine deiminases (PADs). …

Cerebral malaria is a severe complication of malaria. Sequestration of parasitized RBCs in
brain microvasculature is associated with disease pathogenesis, but our understanding of …

Background The hygiene hypothesis suggests an inverse relationship between the incidence
of parasitic infections and chronic inflammatory bowel diseases (IBD). We investigated the …

Schistosomes are parasitic blood flukes that infect approximately 200 million people and are
arguably the most important human helminth in terms of mortality. The outermost surface of …

We have investigated several of the experimental factors that affect calcium phosphate-DNA-mediated
gene transfer of thymidine kinase (tk) into mouse LM tk − Cl 1D cells using …

The role of erythrocyte (red blood cell; RBC) aggregation in affecting leukocyte (white blood
cell; WBC) margination in postcapillary venules of the mesentery (rat) was explored by direct …