User profiles for Martyn D. Winn
 | Martyn WinnSTFC, UK Verified email at stfc.ac.uk Cited by 47427 |
[HTML][HTML] Overview of the CCP4 suite and current developments
The CCP4 (Collaborative Computational Project, Number 4) software suite is a collection of
programs and associated data and software libraries which can be used for macromolecular …
programs and associated data and software libraries which can be used for macromolecular …
[HTML][HTML] Phaser crystallographic software
Phaser is a program for phasing macromolecular crystal structures by both molecular
replacement and experimental phasing methods. The novel phasing algorithms implemented in …
replacement and experimental phasing methods. The novel phasing algorithms implemented in …
[HTML][HTML] REFMAC5 for the refinement of macromolecular crystal structures
This paper describes various components of the macromolecular crystallographic refinement
program REFMAC5, which is distributed as part of the CCP4 suite. REFMAC5 utilizes …
program REFMAC5, which is distributed as part of the CCP4 suite. REFMAC5 utilizes …
Macromolecular TLS refinement in REFMAC at moderate resolutions
Publisher Summary This chapter discusses the translation, rotation, and screw-rotation (TLS)
parameterization of anisotropic displacement parameters (ADPs). In general, each atom …
parameterization of anisotropic displacement parameters (ADPs). In general, each atom …
[HTML][HTML] The CCP4 suite: integrative software for macromolecular crystallography
…, D Waterman, KS Wilson, MD Winn… - … Section D: Structural …, 2023 - scripts.iucr.org
The Collaborative Computational Project No. 4 (CCP4) is a UK-led international collective
with a mission to develop, test, distribute and promote software for macromolecular …
with a mission to develop, test, distribute and promote software for macromolecular …
[HTML][HTML] MrBUMP: an automated pipeline for molecular replacement
RM Keegan, MD Winn - Acta Crystallographica Section D: Biological …, 2008 - iucr.org
A novel automation pipeline for macromolecular structure solution by molecular replacement
is described. There is a special emphasis on the discovery and preparation of a large …
is described. There is a special emphasis on the discovery and preparation of a large …
[HTML][HTML] EGFR oligomerization organizes kinase-active dimers into competent signalling platforms
Epidermal growth factor receptor (EGFR) signalling is activated by ligand-induced receptor
dimerization. Notably, ligand binding also induces EGFR oligomerization, but the structures …
dimerization. Notably, ligand binding also induces EGFR oligomerization, but the structures …
Automated search-model discovery and preparation for structure solution by molecular replacement
RM Keegan, MD Winn - Acta Crystallographica Section D: Biological …, 2007 - scripts.iucr.org
A novel automation pipeline for macromolecular structure solution by molecular replacement
is described. There is a special emphasis on the discovery and preparation of a large …
is described. There is a special emphasis on the discovery and preparation of a large …
AMPLE: a cluster-and-truncate approach to solve the crystal structures of small proteins using rapidly computed ab initio models
Protein ab initio models predicted from sequence data alone can enable the elucidation of
crystal structures by molecular replacement. However, the calculation of such ab initio models …
crystal structures by molecular replacement. However, the calculation of such ab initio models …
[HTML][HTML] Single-molecule imaging and fluorescence lifetime imaging microscopy show different structures for high-and low-affinity epidermal growth factor receptors in …
Epidermal growth factor (EGF) receptor (EGFR) modulates mitosis and apoptosis through
signaling by its high-affinity (HA) and low-affinity (LA) EGF-binding states. The prevailing …
signaling by its high-affinity (HA) and low-affinity (LA) EGF-binding states. The prevailing …