Understanding how signals are integrated to control natural killer (NK) cell responsiveness
in the absence of antigen-specific receptors has been a challenge, but recent work has …

Background CIS43LS is a monoclonal antibody that was shown to protect against controlled
Plasmodium falciparum infection in a phase 1 clinical trial. Whether a monoclonal antibody …

Many cellular responses, such as autoimmunity and cytotoxicity, are controlled by receptors
with cytoplasmic immunoreceptor tyrosine-based inhibition motifs (ITIMs). Here, we showed …

Natural killer (NK) cell inhibitory receptors recruit tyrosine phosphatases to prevent activation,
induce phosphorylation and dissociation of the small adaptor Crk from cytoskeleton …

Several infectious and autoimmune diseases are associated with an expansion of CD21 −
CD27 − atypical B cells (atBCs) that up-regulate inhibitory receptors and exhibit altered B cell …

Binding of NK cell inhibitory receptors to MHC class I (MHC-I) confers increased
responsiveness to NK cells by a process known as NK cell licensing/education. Reduced MHC-I …

IgG antibodies play a role in malaria immunity, but whether and how IgM protects from malaria
and the biology of Plasmodium falciparum (Pf)–specific IgM B cells is unclear. In a Mali …

Interleukin 15 (IL-15) is an essential cytokine for the survival and proliferation of natural killer
(NK) cells. IL-15 activates signaling by the β and common γ (γ c ) chain heterodimer of the IL…

This paper investigates the extraction of acoustic signatures from small boats using a
passive sonar system. Noise radiated from a small boats consists of broadband noise and …

Provides broad coverage of speech audiometry and masking in clinical protocols. In addition
to providing appropriate background information, the coverage presents a broad spectrum …