Elevated postprandial blood glucose levels constitute a global epidemic and a major risk
factor for prediabetes and type II diabetes, but existing dietary methods for controlling them …

Human gut microbiome composition is shaped by multiple factors but the relative contribution
of host genetics remains elusive. Here we examine genotype and microbiome data from …

Empiric probiotics are commonly consumed by healthy individuals as means of life quality
improvement and disease prevention. However, evidence of probiotic gut mucosal …

Obesity, diabetes, and related manifestations are associated with an enhanced, but poorly
understood, risk for mucosal infection and systemic inflammation. Here, we show in mouse …

Probiotics are widely prescribed for prevention of antibiotics-associated dysbiosis and
related adverse effects. However, probiotic impact on post-antibiotic reconstitution of the gut …

Host-microbiome co-evolution drives homeostasis and disease susceptibility, yet regulatory
principles governing the integrated intestinal host-commensal microenvironment remain …

The intestinal microbiota undergoes diurnal compositional and functional oscillations that
affect metabolic homeostasis, but the mechanisms by which the rhythmic microbiota influences …

Mesenchymal stem cells (MSCs) are widespread in adult organisms and may be involved in
tissue maintenance and repair as well as in the regulation of hematopoiesis and …

Innate lymphoid cells (ILCs) are critical modulators of mucosal immunity, inflammation, and
tissue homeostasis, but their full spectrum of cellular states and regulatory landscapes …

Metagenomic sequencing increased our understanding of the role of the microbiome in
health and disease, yet it only provides a snapshot of a highly dynamic ecosystem. Here, we …