We sequenced the genomes of a ∼7,000-year-old farmer from Germany and eight ∼8,000-year-old
hunter-gatherers from Luxembourg and Sweden. We analysed these and other …

The origins of the First Americans remain contentious. Although Native Americans seem to
be genetically most closely related to east Asians 1 , 2 , 3 , there is no consensus with regard …

Native Americans derive from a small number of Asian founders who likely arrived to the
Americas via Beringia. However, additional details about the intial colonization of the Americas …

Objective To use the rs1229984 variant in the alcohol dehydrogenase 1B gene (ADH1B) as
an instrument to investigate the causal role of alcohol in cardiovascular disease. Design …

Background Statins increase the risk of new-onset type 2 diabetes mellitus. We aimed to
assess whether this increase in risk is a consequence of inhibition of 3-hydroxy-3-methylglutaryl…

INTRODUCTION The consensus view on the peopling of the Americas is that ancestors of
modern Native Americans entered the Americas from Siberia via the Bering Land Bridge and …

High-coverage whole-genome sequence studies have so far focused on a limited number 1
of geographically restricted populations 2 , 3 , 4 , 5 , or been targeted at specific diseases, …

The Saami are regarded as extreme genetic outliers among European populations. In this
study, a high-resolution phylogenetic analysis of Saami genetic heritage was undertaken in a …

A large part of Y chromosome lineages in East European and East Asian human populations
belong to haplogroup (hg) NO, which is composed of two sister clades N-M231 and O-…

The Turkic peoples represent a diverse collection of ethnic groups defined by the Turkic
languages. These groups have dispersed across a vast area, including Siberia, Northwest China…