Breast cancers are complex cellular ecosystems where heterotypic interactions play central
roles in disease progression and response to therapy. However, our knowledge of their …

Determining the genome sequence of an organism is challenging, yet fundamental to
understanding its biology. Over the past decade, thousands of human genomes have been …

Objective Agents that antagonize the N-methyl-D-aspartic acid (NMDA) receptor, such as
phencyclidine and ketamine, produce an acute psychotic state in normal individuals that …

Complete knowledge of the genetic variation in individual human genomes is a crucial
foundation for understanding the etiology of disease. Genetic variation is typically characterized …

Objective: The effect of NIDCAP (Newborn Individualized Developmental Care and
Assessment Program) was examined on the neurobehavioral, electrophysiological and …

Quantitative brain tissue segmentation from newborn MRI offers the possibility of improved
clinical decision making and diagnosis, new insight into the mechanisms of disease, and new …

Splicing varies across brain regions, but the single-cell resolution of regional variation is
unclear. We present a single-cell investigation of differential isoform expression (DIE) between …

During neurosurgical procedures the objective of the neurosurgeon is to achieve the resection
of as much diseased tissue as possible while achieving the preservation of healthy brain …

X-linked Dystonia-Parkinsonism (XDP) is a Mendelian neurodegenerative disease that is
endemic to the Philippines and is associated with a founder haplotype. We integrated multiple …

Agents that antagonize the glutamatergic N‐methyl‐d‐aspartate (NMDA) receptor, such as
phenylcyclidine (PCP) and ketamine, produce a behavioral state in healthy volunteers that …