[HTML][HTML] The conjunctival microbiome in health and trachomatous disease: a case control study
Y Zhou, MJ Holland, P Makalo, H Joof, CH Roberts… - Genome medicine, 2014 - Springer
Background Trachoma, caused by Chlamydia trachomatis, remains the worlds leading infectious
cause of blindness. Repeated ocular infection during childhood leads to scarring of the …
cause of blindness. Repeated ocular infection during childhood leads to scarring of the …
Re-emergence of Chlamydia trachomatis infection after mass antibiotic treatment of a trachoma-endemic Gambian community: a longitudinal study
MJ Burton, MJ Holland, P Makalo, EAN Aryee… - The Lancet, 2005 - thelancet.com
Background Community-wide mass antibiotic treatment is a central component of trachoma
control. The optimum frequency and duration of treatment are unknown. We measured the …
control. The optimum frequency and duration of treatment are unknown. We measured the …
[HTML][HTML] Defining seropositivity thresholds for use in trachoma elimination studies
…, PP Rubangakene, H Joof, P Makalo… - PLoS Neglected …, 2017 - journals.plos.org
Background Efforts are underway to eliminate trachoma as a public health problem by 2020.
Programmatic guidelines are based on clinical signs that correlate poorly with Chlamydia …
Programmatic guidelines are based on clinical signs that correlate poorly with Chlamydia …
[HTML][HTML] Mass treatment with azithromycin for trachoma: when is one round enough? Results from the PRET Trial in the Gambia
…, JD Hart, H Joof, M Laye, P Makalo… - PLoS neglected …, 2013 - journals.plos.org
Background The World Health Organization has recommended three rounds of mass drug
administration (MDA) with antibiotics in districts where the prevalence of follicular trachoma (…
administration (MDA) with antibiotics in districts where the prevalence of follicular trachoma (…
[HTML][HTML] Conjunctival MicroRNA expression in inflammatory trachomatous scarring
…, M Rajasekhar, SE Burr, H Joof, P Makalo… - PLoS neglected …, 2013 - journals.plos.org
Purpose Trachoma is a fibrotic disease of the conjunctiva initiated by Chlamydia
trachomatis infection. This blinding disease affects over 40 million people worldwide yet the …
trachomatis infection. This blinding disease affects over 40 million people worldwide yet the …
[HTML][HTML] Profound and Sustained Reduction in Chlamydia trachomatis in The Gambia: A Five-Year Longitudinal Study of Trachoma Endemic Communities
MJ Burton, MJ Holland, P Makalo… - PLoS neglected …, 2010 - journals.plos.org
Background The elimination of blinding trachoma focuses on controlling Chlamydia trachomatis
infection through mass antibiotic treatment and measures to limit transmission. As the …
infection through mass antibiotic treatment and measures to limit transmission. As the …
[HTML][HTML] Trichiasis surgery in The Gambia: a 4-year prospective study
SN Rajak, P Makalo, A Sillah… - … & visual science, 2010 - iovs.arvojournals.org
Purpose.: Trachoma is the leading infectious cause of blindness. Conjunctival Chlamydia
trachomatis infection causes scarring, entropion, trichiasis, and blinding corneal opacification. …
trachomatis infection causes scarring, entropion, trichiasis, and blinding corneal opacification. …
[HTML][HTML] Serology reflects a decline in the prevalence of trachoma in two regions of The Gambia
…, G Cooley, S Gwyn, H Pickering, H Joof, P Makalo… - Scientific reports, 2017 - nature.com
Trachoma is caused by Chlamydia trachomatis (Ct). It is targeted for global elimination as a
public health problem. In 2014, a population-based cross-sectional study was performed in …
public health problem. In 2014, a population-based cross-sectional study was performed in …
Sustainability and acceptability of latrine provision in The Gambia
VM Simms, P Makalo, RL Bailey… - Transactions of the …, 2005 - academic.oup.com
All households in 32 villages were provided with improved pit latrines as part of a trachoma
control programme in a rural part of The Gambia. Latrine provision was externally driven and …
control programme in a rural part of The Gambia. Latrine provision was externally driven and …
[HTML][HTML] Longitudinal changes in tear cytokines and antimicrobial proteins in trachomatous disease
…, P Massae, A Malissa, H Joof, P Makalo… - PLOS Neglected …, 2023 - journals.plos.org
Background Trachoma is a neglected tropical disease caused by ocular infection with
Chlamydia trachomatis, where repeated infections and chronic inflammation can ultimately result …
Chlamydia trachomatis, where repeated infections and chronic inflammation can ultimately result …