Presynaptic α2δ-3 is required for synaptic morphogenesis independent of its Ca2+-channel functions
PT Kurshan, A Oztan, TL Schwarz - Nature neuroscience, 2009 - nature.com
Synaptogenesis involves the transformation of a growth cone into synaptic boutons specialized
for transmitter release. In Drosophila embryos lacking the α 2 δ-3 subunit of presynaptic, …
for transmitter release. In Drosophila embryos lacking the α 2 δ-3 subunit of presynaptic, …
Prevalent presence of periodic actin–spectrin-based membrane skeleton in a broad range of neuronal cell types and animal species
…, Z Wu, MA Carrasco, PT Kurshan… - Proceedings of the …, 2016 - National Acad Sciences
Actin, spectrin, and associated molecules form a periodic, submembrane cytoskeleton in the
axons of neurons. For a better understanding of this membrane-associated periodic …
axons of neurons. For a better understanding of this membrane-associated periodic …
A Drosophila kinesin required for synaptic bouton formation and synaptic vesicle transport
E Pack-Chung, PT Kurshan, DK Dickman… - Nature …, 2007 - nature.com
The morphological transition of growth cones to synaptic boutons characterizes synaptogenesis.
Here we have isolated mutations in immaculate connections (imac; CG8566), a …
Here we have isolated mutations in immaculate connections (imac; CG8566), a …
Synaptogenic pathways
PT Kurshan, K Shen - Current opinion in neurobiology, 2019 - Elsevier
… Author links open overlay panel Peri T Kurshan 3 , Kang Shen 1 2 … Enustun, T. Ejikeme,
R.-R. … PT Kurshan, AQ Phan, GJ Wang, MM Crane, H. Lu, K. Shen …
R.-R. … PT Kurshan, AQ Phan, GJ Wang, MM Crane, H. Lu, K. Shen …
Locomotor activity is regulated by D2‐like receptors in Drosophila: an anatomic and functional analysis
I Draper, PT Kurshan, E McBride… - Developmental …, 2007 - Wiley Online Library
In mammals, dopamine 2-like receptors are expressed in distinct pathways within the central
nervous system, as well as in peripheral tissues. Selected neuronal D2-like receptors play …
nervous system, as well as in peripheral tissues. Selected neuronal D2-like receptors play …
Autonomous screening of C. elegans identifies genes implicated in synaptogenesis
Morphometric studies in multicellular organisms are generally performed manually because
of the complexity of multidimensional features and lack of appropriate tools for handling …
of the complexity of multidimensional features and lack of appropriate tools for handling …
Characterization of a D2-like dopamine receptor (AmDOP3) in honey bee, Apis mellifera
KT Beggs, IS Hamilton, PT Kurshan, JA Mustard… - Insect biochemistry and …, 2005 - Elsevier
Dopamine is an important neurotransmitter in vertebrate and invertebrate nervous systems
and is widely distributed in the brain of the honey bee, Apis mellifera. We report here the …
and is widely distributed in the brain of the honey bee, Apis mellifera. We report here the …
Clarinet (CLA-1), a novel active zone protein required for synaptic vesicle clustering and release
10.7554/eLife.29276.001 Active zone proteins cluster synaptic vesicles at presynaptic
terminals and coordinate their release. In forward genetic screens, we isolated a novel …
terminals and coordinate their release. In forward genetic screens, we isolated a novel …
Mutations in a Drosophila α2δ voltage-gated calcium channel subunit reveal a crucial synaptic function
DK Dickman, PT Kurshan, TL Schwarz - Journal of Neuroscience, 2008 - Soc Neuroscience
Voltage-dependent calcium channels regulate many aspects of neuronal biology, including
synaptic transmission. In addition to their α 1 subunit, which encodes the essential voltage …
synaptic transmission. In addition to their α 1 subunit, which encodes the essential voltage …
[PDF][PDF] γ-Neurexin and frizzled mediate parallel synapse assembly pathways antagonized by receptor endocytosis
Synapse formation defines neuronal connectivity and is thus essential for neuronal circuit
assembly. Trans-synaptic interactions of cell adhesion molecules are thought to induce …
assembly. Trans-synaptic interactions of cell adhesion molecules are thought to induce …