User profiles for Peter J. Schüffler

Peter J. Schüffler

TUM
Verified email at tum.de
Cited by 3924

Highly multiplexed imaging of tumor tissues with subcellular resolution by mass cytometry

…, N Zivanovic, A Jacobs, B Hattendorf, PJ Schüffler… - Nature …, 2014 - nature.com
Mass cytometry enables high-dimensional, single-cell analysis of cell type and state. In
mass cytometry, rare earth metals are used as reporters on antibodies. Analysis of metal …

[HTML][HTML] Validation of a digital pathology system including remote review during the COVID-19 pandemic

…, O Ardon, D Kim, SJ Sirintrapun, PJ Schüffler… - Modern Pathology, 2020 - Elsevier
Remote digital pathology allows healthcare systems to maintain pathology operations
during public health emergencies. Existing Clinical Laboratory Improvement Amendments …

[HTML][HTML] Whole slide imaging equivalency and efficiency study: experience at a large academic center

…, L Corsale, E Stamelos, Y Yagi, PJ Schüffler… - Modern Pathology, 2019 - Elsevier
Whole slide imaging is Food and Drug Administration-approved for primary diagnosis in the
United States of America; however, relatively few pathology departments in the country have …

Deep learning methods for lung cancer segmentation in whole-slide histopathology images—the acdc@ lunghp challenge 2019

…, Y Jiang, L Yu, Z Liu, D Li, PJ Schüffler… - IEEE Journal of …, 2020 - ieeexplore.ieee.org
Accurate segmentation of lung cancer in pathology slides is a critical step in improving patient
care. We proposed the ACDC@LungHP (Automatic Cancer Detection and Classification …

[HTML][HTML] Prognostic relevance of Wnt-inhibitory factor-1 (WIF1) and Dickkopf-3 (DKK3) promoter methylation in human breast cancer

J Veeck, PJ Wild, T Fuchs, PJ Schüffler, A Hartmann… - BMC cancer, 2009 - Springer
Background Secreted Wnt signaling antagonists have recently been described as frequent
targets of epigenetic inactivation in human tumor entities. Since gene silencing of certain Wnt …

Clinical validation of artificial intelligence–augmented pathology diagnosis demonstrates significant gains in diagnostic accuracy in prostate cancer detection

…, J Viret, D Lee, PJ Schüffler… - … of Pathology & …, 2023 - meridian.allenpress.com
Context.— Prostate cancer diagnosis rests on accurate assessment of tissue by a pathologist.
The application of artificial intelligence (AI) to digitized whole slide images (WSIs) can aid …

Integrated digital pathology at scale: a solution for clinical diagnostics and cancer research at a large academic medical center

PJ Schüffler, L Geneslaw… - Journal of the …, 2021 - academic.oup.com
Objective Broad adoption of digital pathology (DP) is still lacking, and examples for DP
connecting diagnostic, research, and educational use cases are missing. We blueprint a holistic …

Prediction of colorectal cancer diagnosis based on circulating plasma proteins

S Surinova, M Choi, S Tao, PJ Schüffler… - EMBO molecular …, 2015 - embopress.org
Non‐invasive detection of colorectal cancer with blood‐based markers is a critical clinical
need. Here we describe a phased mass spectrometry‐based approach for the discovery, …

Automatic detection and segmentation of Crohn's disease tissues from abdominal MRI

D Mahapatra, PJ Schüffler… - IEEE transactions on …, 2013 - ieeexplore.ieee.org
We propose an information processing pipeline for segmenting parts of the bowel in abdominal
magnetic resonance images that are affected with Crohn's disease. Given a magnetic …

[HTML][HTML] TMARKER: A free software toolkit for histopathological cell counting and staining estimation

PJ Schüffler, TJ Fuchs, CS Ong, PJ Wild… - Journal of pathology …, 2013 - Elsevier
Background: Histological tissue analysis often involves manual cell counting and staining
estimation of cancerous cells. These assessments are extremely time consuming, highly …