The formation of coat protein complex I (COPI)–coated vesicles is regulated by the small
guanosine triphosphatase (GTPase) adenosine diphosphate ribosylation factor 1 (Arf1), which …

The optic fissure is a transient gap in the developing vertebrate eye, which must be closed as
development proceeds. A persisting optic fissure, coloboma, is a major cause for blindness …

The zebrafish pronephros model, using morpholino oligonucleotides (MO) to deplete target
genes, has been extensively used to characterize human ciliopathy phenotypes. Recently, …

COPI (coat protein I)‐coated vesicles are implicated in various transport steps within the
early secretory pathway. The major structural component of the COPI coat is the heptameric …

Colobomata, persistent optic fissures, frequently cause congenital blindness. Here, we
focused on optic fissure fusion using in vivo time-lapse imaging in zebrafish. We identified the …

Optic cup morphogenesis is an intricate process. Especially, the formation of the optic fissure
is not well understood. Persisting optic fissures, termed coloboma, are frequent causes for …

The corpuscles of Stannius (CS) represent a unique endocrine organ of teleostean fish that
secrets stanniocalcin-1 (Stc1) to maintain calcium homeostasis. Appearing at 20–25 somite …

Nephronophthisis (NPH), an autosomal recessive ciliopathy, results from mutations in more
than 20 different genes (NPHPs). These gene products form protein complexes that regulate …

The optic fissure is a transient gap in the developing optic cup of vertebrates. Persisting optic
fissures, coloboma, are a frequent reason for blindness in children. Although many genes …

The optic fissure is a transient gap in the developing vertebrate eye, which must be closed as
development proceeds. A persisting optic fissure, coloboma, is a major cause for blindness …