User profiles for Razvan C. Stan
Razvan C. StanProfessor, Chonnam National University Verified email at jnu.ac.kr Cited by 241 |
Febrile temperatures modulate the formation of immune complexes relevant for autoimmune diseases
Background Autoimmune disorders encompass a diverse subset of diseases whose common
symptoms include, among others, fever. Fever of unknown origins, once an infectious or …
symptoms include, among others, fever. Fever of unknown origins, once an infectious or …
[HTML][HTML] Febrile temperatures increase in vitro antibody affinity for malarial and dengue antigens
… overnight at 37C, 40C or 42C with a … 37C or 40C. After a new wash cycle, the anti-NS1 mAb
4F6 [14] was diluted (log2) starting at 157.3 nM, added to wells and incubated at 37C or 40C …
4F6 [14] was diluted (log2) starting at 157.3 nM, added to wells and incubated at 37C or 40C …
Cellular Adaptation Relies on Regulatory Proteins Having Episodic Memory: Proteins Modulate Cell Metabolism and Reproduction by Remembering, Transmitting …
The ability to memorize changes in the environment is present at all biological levels, from
social groups and individuals, down to single cells. Trans‐generational memory is embedded …
social groups and individuals, down to single cells. Trans‐generational memory is embedded …
ThermoPCD: a database of molecular dynamics trajectories of antibody–antigen complexes at physiologic and fever-range temperatures
PK Singh, RC Stan - Database, 2024 - academic.oup.com
… to 2C higher than the average physiological temperature (9). … and fever-range temperatures
(38C–40C, 311 K–313 K) are on … at 40C as opposed to the data obtained at 37C in vitro (10), …
(38C–40C, 311 K–313 K) are on … at 40C as opposed to the data obtained at 37C in vitro (10), …
Fluorescent Detection of Fluid Phase Endocytosis Allows for In Vivo Estimation of Endocytic Vesicle Sizes in Plant Cells with Sub‐Diffraction Accuracy
Using the bright, photostable, charged and hydrophilic fluorescent dye Alexa 488 hydrazide
to label the fluid phase around intact guard cells, we show that these cells incorporate the …
to label the fluid phase around intact guard cells, we show that these cells incorporate the …
Rheumatoid arthritis autoantibodies benefit from inflammation temperatures
… Here, using molecular dynamics simulations, we seek to address the role of febrile and
inflammation relevant temperatures (38 C-39 C) on the structural stability and the functional …
inflammation relevant temperatures (38 C-39 C) on the structural stability and the functional …
[HTML][HTML] Fever as an evolutionary agent to select immune complexes interfaces
… temperature (20–25 C) or at 4–8 C, without explicitly considering the potential impact of the
physiological temperature. Indeed, when assays are performed at 37 C on living cells and in …
physiological temperature. Indeed, when assays are performed at 37 C on living cells and in …
[HTML][HTML] Temporal modulation of drug desensitization procedures
RC Stan - Current Issues in Molecular Biology, 2022 - mdpi.com
… LAT1 will further activate PLCγ-2 (phospholipase C Gamma) that helps hydrolyze cell … In
turn, DAG interacts with DAG-dependent isoforms of cytosolic PKC (protein kinase C) that will …
turn, DAG interacts with DAG-dependent isoforms of cytosolic PKC (protein kinase C) that will …
Enhanced binding at fever temperatures of HER2 in complex with trastuzumab and pertuzumab
Aim: Fever follows the administration of trastuzumab and pertuzumab used in HER2-relevant
immunotherapy, but is often eliminated in clinical practice. This work explores the role of …
immunotherapy, but is often eliminated in clinical practice. This work explores the role of …
[HTML][HTML] A mathematical model relates intracellular TLR4 oscillations to sepsis progression
Objective Oscillations of physiological parameters describe many biological processes and
their modulation is determinant for various pathologies. In sepsis, toll-like receptor 4 (TLR4) …
their modulation is determinant for various pathologies. In sepsis, toll-like receptor 4 (TLR4) …