Apolipoprotein E is a plasma protein that serves as a ligand for low density lipoprotein
receptors and, through its interaction with these receptors, participates in the transport of …

First recognized as a major determinant in lipoprotein metabolism and cardiovascular
disease, apolipoprotein (apo) E has emerged as an important molecule in several biological …

We sequenced the genomes of a ∼7,000-year-old farmer from Germany and eight ∼8,000-year-old
hunter-gatherers from Luxembourg and Sweden. We analysed these and other …

… II revzezo Plasma lipoproteins: apolipoprotein structure and function Robert W. Mahley, … ,
but it seems likely that the amphiphilic helical Mahley et ai. Apolipoproteins 1485 structures are …

The premise of this review is that apolipoprotein (apo) E4 is much more than a contributing
factor to neurodegeneration. ApoE has critical functions in redistributing lipids among CNS …

The plasma protein apolipoprotein (apo) E is an important determinant of lipid transport and
metabolism in mammals. In the present study, immunocytochemistry has been used to …

We have previously demonstrated that astrocytes synthesize and secrete apolipoprotein E
in situ. In the present work, primary cultures of rat brain astrocytes were used to study …

The plasma clearance of intestinally derived remnant lipoproteins by the liver is a process
that likely involves three steps. Our model suggests that the initial rapid clearance by the liver …

Human apolipoprotein E, a blood plasma protein, mediates the transport and uptake of
cholesterol and lipid by way of its high affinity interaction with different cellular receptors, …

Blood lipids are transported in soluble, lipidprotein complexes (lipoproteins), which include
protein components called apolipoproteins. The lipoproteins, of which there are four main …