Construction of short tandem target mimic (STTM) to block the functions of plant and animal microRNAs
Small RNAs are widespread in plants and animals. They largely include microRNAs (miRNAs)
and short interfering RNAs (siRNAs), and they play key roles in gene and chromatin …
and short interfering RNAs (siRNAs), and they play key roles in gene and chromatin …
[PDF][PDF] Two pan-SARS-CoV-2 nanobodies and their multivalent derivatives effectively prevent Omicron infections in mice
With the widespread vaccinations against coronavirus disease 2019 (COVID-19), we are
witnessing gradually waning neutralizing antibodies and increasing cases of breakthrough …
witnessing gradually waning neutralizing antibodies and increasing cases of breakthrough …
Coat color determination by miR-137 mediated down-regulation of microphthalmia-associated transcription factor in a mouse model
C Dong, H Wang, L Xue, Y Dong, L Yang, R Fan, X Yu… - Rna, 2012 - rnajournal.cshlp.org
Coat color is a key economic trait in wool-producing species. Color development and
pigmentation are controlled by complex mechanisms in animals. Here, we report the first …
pigmentation are controlled by complex mechanisms in animals. Here, we report the first …
A novel nanobody targeting Middle East respiratory syndrome coronavirus (MERS-CoV) receptor-binding domain has potent cross-neutralizing activity and protective …
…, Y Chen, Y Guo, Y Wang, J Shang, K Ji, R Fan… - Journal of …, 2018 - Am Soc Microbiol
The newly emerged Middle East respiratory syndrome coronavirus (MERS-CoV) continues
to infect humans and camels, calling for efficient, cost-effective, and broad-spectrum …
to infect humans and camels, calling for efficient, cost-effective, and broad-spectrum …
[PDF][PDF] An updated view of leptin on implantation and pregnancy: a review
M Herrid, SKA Palanisamy, UA Ciller, R Fan… - Physiological …, 2014 - researchgate.net
The hormone leptin, which is thought to be primarily produced by adipose tissue, is a
polypeptide that was initially characterized by its ability to regulate food intake and energy …
polypeptide that was initially characterized by its ability to regulate food intake and energy …
[HTML][HTML] Skin transcriptome profiles associated with coat color in sheep
R Fan, J Xie, J Bai, H Wang, X Tian, R Bai, X Jia… - BMC genomics, 2013 - Springer
Background Previous molecular genetic studies of physiology and pigmentation of sheep
skin have focused primarily on a limited number of genes and proteins. To identify additional …
skin have focused primarily on a limited number of genes and proteins. To identify additional …
[HTML][HTML] Genomic analysis of the domestication and post-Spanish conquest evolution of the llama and alpaca
R Fan, Z Gu, X Guang, JC Marín, V Varas, BA González… - Genome biology, 2020 - Springer
Background Despite their regional economic importance and being increasingly reared
globally, the origins and evolution of the llama and alpaca remain poorly understood. Here we …
globally, the origins and evolution of the llama and alpaca remain poorly understood. Here we …
[HTML][HTML] MicroRNA-21a-5p functions on the regulation of melanogenesis by targeting Sox5 in mouse skin melanocytes
P Wang, Y Zhao, R Fan, T Chen, C Dong - International Journal of …, 2016 - mdpi.com
MicroRNAs (miRNAs) play an important role in regulating almost all biological processes.
miRNAs bind to the 3′ untranslated region (UTR) of mRNAs by sequence matching. In a …
miRNAs bind to the 3′ untranslated region (UTR) of mRNAs by sequence matching. In a …
[HTML][HTML] Identification and characterization of microRNAs in white and brown alpaca skin
X Tian, J Jiang, R Fan, H Wang, X Meng, X He, J He… - BMC genomics, 2012 - Springer
Background MicroRNAs (miRNAs) are small, non-coding 21–25 nt RNA molecules that play
an important role in regulating gene expression. Little is known about the expression …
an important role in regulating gene expression. Little is known about the expression …
[HTML][HTML] MicroRNA-27a-3p inhibits melanogenesis in mouse skin melanocytes by targeting Wnt3a
…, P Wang, J Meng, Y Ji, D Xu, T Chen, R Fan… - International journal of …, 2015 - mdpi.com
MicroRNAs (miRNAs) play an essential role in the regulation of almost all the biological
processes, including melanogenesis. MiR-27a-3p is nearly six times higher in white alpaca skin …
processes, including melanogenesis. MiR-27a-3p is nearly six times higher in white alpaca skin …