In the age of stem cell engineering it is critical to understand how stem cell activity is regulated
during regeneration. Hairs are mini-organs that undergo cyclic regeneration throughout …

The dynamic behavior of epithelial cell sheets plays a central role during numerous developmental
processes. Genetic and imaging studies of epithelial morphogenesis in a wide range …

Vertebrate embryos are characterized by an elongated antero-posterior (AP) body axis, which
forms by progressive cell deposition from a posterior growth zone in the embryo. Here, we …

Ninety per cent of the world's data have been generated in the last 5 years (Machine learning:
the power and promise of computers that learn by example. Report no. DES4702. Issued …

One of the fundamental questions in developmental biology is how the vast range of pattern
and structure we observe in nature emerges from an almost uniformly homogeneous …

Stem cells cycle through active and quiescent states. Large populations of stem cells in an
organ may cycle randomly or in a coordinated manner. Although stem cell cycling within …

Biological pattern formation. Two mechanisms can show similar results.(Left) Outcome of a
reactiondiffusion model (7) in which activator and inhibitor react and diffuse. Small random …

Long-distance cell migration is an important feature of embryonic development, adult
morphogenesis and cancer, yet the mechanisms that drive subpopulations of cells to distinct …

The purpose of this perspective is to highlight the merit of the reptile integument as an
experimental model. Reptiles represent the first amniotes. From stem reptiles, extant reptiles, birds …

Each vertebrate species displays specific tooth patterns in each quadrant of the jaw: the
mouse has one incisor and three molars, which develop at precise locations and at different …